| 51 | 12435745 | Expression and characterization of recombinant human UDP-glucuronosyltransferases (UGTs). UGT1A9 is more resistant to detergent inhibition than other UGTs and was purified as an active dimeric enzyme. | J Biol Chem | 2003 Feb 7 |
1 |
| 52 | 12485951 | Acyl glucuronidation and glucosidation of a new and selective endothelin ET(A) receptor antagonist in human liver microsomes. | Drug Metab Dispos | 2003 Jan |
4 |
| 53 | 12487149 | Predicting pharmacokinetics and drug interactions in patients from in vitro and in vivo models: the experience with 5,6-dimethylxanthenone-4-acetic acid (DMXAA), an anti-cancer drug eliminated mainly by conjugation. | Drug Metab Rev | 2002 Nov |
7 |
| 54 | 12519692 | Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: human UDP-glucuronosyltransferase enzymes involved in lactonization. | Xenobiotica | 2003 Jan |
1 |
| 55 | 12527334 | Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7. | Biochem Pharmacol | 2003 Feb 1 |
6 |
| 56 | 12527799 | Opioids bind to the amino acids 84 to 118 of UDP-glucuronosyltransferase UGT2B7. | Mol Pharmacol | 2003 Feb |
2 |
| 57 | 12623074 | Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7. | Arch Biochem Biophys | 2003 Mar 15 |
1 |
| 58 | 12629580 | Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients. | Pharmacogenomics J | 2003 |
2 |
| 59 | 12657745 | Glucuronidation of 1'-hydroxyestragole (1'-HE) by human UDP-glucuronosyltransferases UGT2B7 and UGT1A9. | Toxicol Sci | 2003 May |
6 |
| 60 | 12695347 | Glucuronidation of etoposide in human liver microsomes is specifically catalyzed by UDP-glucuronosyltransferase 1A1. | Drug Metab Dispos | 2003 May |
1 |
| 61 | 12695355 | Involvement of human UGT2B7 and 2B15 in rofecoxib metabolism. | Drug Metab Dispos | 2003 May |
5 |
| 62 | 12695358 | Sequence variability and candidate gene analysis in two cancer patients with complex clinical outcomes during morphine therapy. | Drug Metab Dispos | 2003 May |
2 |
| 63 | 12732356 | The effect of valproic acid on drug and steroid glucuronidation by expressed human UDP-glucuronosyltransferases. | Biochem Pharmacol | 2003 May 1 |
2 |
| 64 | 12746330 | Human uridine diphosphate-glucuronosyltransferase UGT2B7 conjugates mineralocorticoid and glucocorticoid metabolites. | Endocrinology | 2003 Jun |
2 |
| 65 | 12756209 | The effect of incubation conditions on the enzyme kinetics of udp-glucuronosyltransferases. | Drug Metab Dispos | 2003 Jun |
4 |
| 66 | 12811366 | A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine. | Clin Pharmacol Ther | 2003 Jun |
6 |
| 67 | 12920162 | Isoform selectivity and kinetics of morphine 3- and 6-glucuronidation by human udp-glucuronosyltransferases: evidence for atypical glucuronidation kinetics by UGT2B7. | Drug Metab Dispos | 2003 Sep |
2 |
| 68 | 12920168 | Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism. | Drug Metab Dispos | 2003 Sep |
12 |
| 69 | 14508389 | Interpretation of the presence of 6-monoacetylmorphine in the absence of morphine-3-glucuronide in urine samples: evidence of heroin abuse. | Ther Drug Monit | 2003 Oct |
2 |
| 70 | 14575648 | Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity. | Toxicol Appl Pharmacol | 2003 Nov 1 |
3 |
| 71 | 14667942 | Evidence that unsaturated fatty acids are potent inhibitors of renal UDP-glucuronosyltransferases (UGT): kinetic studies using human kidney cortical microsomes and recombinant UGT1A9 and UGT2B7. | Biochem Pharmacol | 2004 Jan 1 |
1 |
| 72 | 14744946 | Involvement of human hepatic UGT1A1, UGT2B4, and UGT2B7 in the glucuronidation of carvedilol. | Drug Metab Dispos | 2004 Feb |
4 |
| 73 | 14746343 | Formation of highly analgesic morphine-6-glucuronide following physiologic concentration of morphine in human brain. | J Toxicol Sci | 2003 Dec |
1 |
| 74 | 14977865 | Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia). | Drug Metab Dispos | 2004 Mar |
3 |
| 75 | 15001974 | A novel functional polymorphism in the uridine diphosphate-glucuronosyltransferase 2B7 promoter with significant impact on promoter activity. | Clin Pharmacol Ther | 2004 Mar |
3 |
| 76 | 15018021 | Interindividual variation in the ratio between plasma morphine and its metabolites in cancer patients. | Int J Clin Pharmacol Res | 2003 |
2 |
| 77 | 15047194 | Glucuronidation of carboxylic acid containing compounds by UDP-glucuronosyltransferase isoforms. | Arch Biochem Biophys | 2004 Apr 15 |
5 |
| 78 | 15100177 | Amide N-glucuronidation of MaxiPost catalyzed by UDP-glucuronosyltransferase 2B7 in humans. | Drug Metab Dispos | 2004 May |
7 |
| 79 | 15135306 | Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4. | Biochem Pharmacol | 2004 Jun 1 |
1 |
| 80 | 15292462 | N-glucuronidation of carbamazepine in human tissues is mediated by UGT2B7. | J Pharmacol Exp Ther | 2004 Dec |
7 |
| 81 | 15319348 | Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population. | Drug Metab Dispos | 2004 Sep |
4 |
| 82 | 15320866 | Farnesol is glucuronidated in human liver, kidney and intestine in vitro, and is a novel substrate for UGT2B7 and UGT1A1. | Biochem J | 2004 Dec 15 |
2 |
| 83 | 15470160 | Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes. | Drug Metab Dispos | 2005 Jan |
6 |
| 84 | 15470161 | Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism. | Drug Metab Dispos | 2005 Jan |
1 |
| 85 | 15547048 | Sertraline is metabolized by multiple cytochrome P450 enzymes, monoamine oxidases, and glucuronyl transferases in human: an in vitro study. | Drug Metab Dispos | 2005 Feb |
1 |
| 86 | 15608137 | Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform. | Drug Metab Dispos | 2005 Mar |
6 |
| 87 | 15611481 | Modulation of UDP-glucuronosyltransferase function by cytochrome P450: evidence for the alteration of UGT2B7-catalyzed glucuronidation of morphine by CYP3A4. | Mol Pharmacol | 2005 Mar |
9 |
| 88 | 15615884 | An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China. | Toxicol Sci | 2005 May |
6 |
| 89 | 15821044 | Lithocholic acid decreases expression of UGT2B7 in Caco-2 cells: a potential role for a negative farnesoid X receptor response element. | Drug Metab Dispos | 2005 Jul |
13 |
| 90 | 15980101 | Udp-glucuronosyltransferase 2b7 is the major enzyme responsible for gemcabene glucuronidation in human liver microsomes. | Drug Metab Dispos | 2005 Sep |
9 |
| 91 | 15988124 | Identification of human UDP-glucuronosyltransferase isoform(s) responsible for the glucuronidation of 2-(4-chlorophenyl)- 5-(2-furyl)-4-oxazoleacetic acid (TA-1801A). | Drug Metab Pharmacokinet | 2005 Jun |
5 |
| 92 | 16045647 | Genetic variability and clinical efficacy of morphine. | Acta Anaesthesiol Scand | 2005 Aug |
3 |
| 93 | 16049128 | Altered AZT (3'-azido-3'-deoxythymidine) glucuronidation kinetics in liver microsomes as an explanation for underprediction of in vivo clearance: comparison to hepatocytes and effect of incubation environment. | Drug Metab Dispos | 2005 Nov |
6 |
| 94 | 16051636 | Isoflavones modulate the glucuronidation of estradiol in human liver microsomes. | Carcinogenesis | 2005 Dec |
2 |
| 95 | 16103897 | Clinical response to morphine in cancer patients and genetic variation in candidate genes. | Pharmacogenomics J | 2005 |
2 |
| 96 | 16129696 | Glycosidation of an endothelin ET(A) receptor antagonist and diclofenac in human liver microsomes: aglycone-dependent UDP-sugar selectivity. | Drug Metab Dispos | 2005 Dec |
10 |
| 97 | 16141602 | Interindividual variability in nicotine metabolism: C-oxidation and glucuronidation. | Drug Metab Pharmacokinet | 2005 Aug |
2 |
| 98 | 16166450 | Effects of ketoconazole on glucuronidation by UDP-glucuronosyltransferase enzymes. | Clin Cancer Res | 2005 Sep 15 |
3 |
| 99 | 16187975 | S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen. | Br J Clin Pharmacol | 2005 Oct |
2 |
| 100 | 16215614 | [Genetic variation-- important for the clinical effect of opioids?]. | Tidsskr Nor Laegeforen | 2005 Oct 6 |
1 |