| 1 | 11741986 | Spinesin/TMPRSS5, a novel transmembrane serine protease, cloned from human spinal cord. | J Biol Chem | 2002 Mar 1 |
3 |
| 2 | 11745466 | The TMPRSS2 gene encoding transmembrane serine protease is overexpressed in a majority of prostate cancer patients: detection of mutated TMPRSS2 form in a case of aggressive disease. | Int J Cancer | 2001 Dec 1 |
1 |
| 3 | 12711008 | Characterisation of gene expression patterns in 22RV1 cells for determination of environmental androgenic/antiandrogenic compounds. | J Steroid Biochem Mol Biol | 2003 Feb |
5 |
| 4 | 15537383 | The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells. | Biochem J | 2005 Jun 15 |
2 |
| 5 | 18471784 | Inactivation of androgens by UDP-glucuronosyltransferases in the human prostate. | Best Pract Res Clin Endocrinol Metab | 2008 Apr |
1 |
| 6 | 18474293 | Detection of the TMPRSS2-ETS fusion gene in prostate carcinomas: retrospective analysis of 55 formalin-fixed and paraffin-embedded samples with clinical data. | Cancer Genet Cytogenet | 2008 May |
2 |
| 7 | 18719366 | Androgen responsive and refractory prostate cancer cells exhibit distinct curcumin regulated transcriptome. | Cancer Biol Ther | 2008 Sep |
1 |
| 8 | 19293179 | SLC45A3-ELK4 is a novel and frequent erythroblast transformation-specific fusion transcript in prostate cancer. | Cancer Res | 2009 Apr 1 |
2 |
| 9 | 19339269 | Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer. | Cancer Res | 2009 Apr 1 |
1 |
| 10 | 19584279 | Reactivation of androgen receptor-regulated TMPRSS2:ERG gene expression in castration-resistant prostate cancer. | Cancer Res | 2009 Aug 1 |
3 |
| 11 | 20124490 | Variability in the androgen response of prostate epithelium to 5alpha-reductase inhibition: implications for prostate cancer chemoprevention. | Cancer Res | 2010 Feb 15 |
1 |
| 12 | 20147525 | 1{alpha},25-Dihydroxyvitamin D3 inhibits growth of VCaP prostate cancer cells despite inducing the growth-promoting TMPRSS2:ERG gene fusion. | Endocrinology | 2010 Apr |
2 |
| 13 | 20382709 | TMPRSS2, a serine protease expressed in the prostate on the apical surface of luminal epithelial cells and released into semen in prostasomes, is misregulated in prostate cancer cells. | Am J Pathol | 2010 Jun |
1 |
| 14 | 20601956 | Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements. | Nat Genet | 2010 Aug |
1 |
| 15 | 20616363 | Detection of TMPRSS2-ETS fusions by a multiprobe fluorescence in situ hybridization assay for the early diagnosis of prostate cancer: a pilot study. | J Mol Diagn | 2010 Sep |
1 |
| 16 | 20631123 | TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus in Caco-2 cells. | J Virol | 2010 Oct |
2 |
| 17 | 20736744 | Detection of TMPRSS2 gene deletions and translocations in carcinoma, intraepithelial neoplasia, and normal epithelium of the prostate by direct fluorescence in situ hybridization. | Diagn Mol Pathol | 2010 Sep |
4 |
| 18 | 21178489 | ERG oncogene modulates prostaglandin signaling in prostate cancer cells. | Cancer Biol Ther | 2011 Feb 15 |
4 |
| 19 | 21394739 | TMPRSS2/ERG fusion gene expression alters chemo- and radio-responsiveness in cell culture models of androgen independent prostate cancer. | Prostate | 2011 Oct 1 |
1 |
| 20 | 21519790 | Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells. | Int J Oncol | 2011 Jul |
2 |
| 21 | 21802835 | TMPRSS2-ERG status in circulating tumor cells as a predictive biomarker of sensitivity in castration-resistant prostate cancer patients treated with abiraterone acetate. | Eur Urol | 2011 Nov |
2 |
| 22 | 22154085 | Cryptotanshinone suppresses androgen receptor-mediated growth in androgen dependent and castration resistant prostate cancer cells. | Cancer Lett | 2012 Mar |
2 |
| 23 | 22212979 | Androgen receptor overexpression alters binding dynamics of the receptor to chromatin and chromatin structure. | Prostate | 2012 Aug 1 |
1 |
| 24 | 22313860 | Phase II study of cytarabine in men with docetaxel-refractory, castration-resistant prostate cancer with evaluation of TMPRSS2-ERG and SPINK1 as serum biomarkers. | BJU Int | 2012 Sep |
1 |
| 25 | 22415461 | Role of dutasteride in pre-clinical ETS fusion-positive prostate cancer models. | Prostate | 2012 Oct 1 |
2 |
| 26 | 22558251 | Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts. | PLoS One | 2012 |
1 |
| 27 | 23072892 | Hemagglutinin activating host cell proteases provide promising drug targets for the treatment of influenza A and B virus infections. | Vaccine | 2012 Dec 7 |
4 |
| 28 | 23192983 | Prostaglandin 15d-PGJ(2) inhibits androgen receptor signaling in prostate cancer cells. | Mol Endocrinol | 2013 Feb |
4 |
| 29 | 23251544 | Chemical biology drug sensitivity screen identifies sunitinib as synergistic agent with disulfiram in prostate cancer cells. | PLoS One | 2012 |
2 |
| 30 | 23395110 | Novel symmetrical ureas as modulators of protein arginine methyl transferases. | Bioorg Med Chem | 2013 Apr 1 |
1 |
| 31 | 23399562 | Fenofibrate down-regulates the expressions of androgen receptor (AR) and AR target genes and induces oxidative stress in the prostate cancer cell line LNCaP. | Biochem Biophys Res Commun | 2013 Mar 8 |
1 |
| 32 | 23527573 | Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation. | Biochem J | 2013 Jun 1 |
1 |
| 33 | 23554889 | Celastrol suppresses tumor cell growth through targeting an AR-ERG-NF-κB pathway in TMPRSS2/ERG fusion gene expressing prostate cancer. | PLoS One | 2013 |
1 |
| 34 | 23565244 | PARP inhibition sensitizes to low dose-rate radiation TMPRSS2-ERG fusion gene-expressing and PTEN-deficient prostate cancer cells. | PLoS One | 2013 |
1 |
| 35 | 24227843 | TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein. | J Virol | 2014 Jan |
4 |
| 36 | 24505269 | TMPRSS2-ERG expression predicts prostate cancer survival and associates with stromal biomarkers. | PLoS One | 2014 |
1 |
| 37 | 24527392 | Conserved two-step regulatory mechanism of human epithelial differentiation. | Stem Cell Reports | 2014 Feb 11 |
2 |
| 38 | 24600012 | The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses. | J Virol | 2014 May |
1 |
| 39 | 24764242 | Hypermethylation-mediated transcriptional repression of TMPRSS2 in androgen receptor-negative prostate cancer cells. | Exp Biol Med (Maywood) | 2014 Jul |
1 |
| 40 | 24824408 | Androgen receptor CAG repeat length and TMPRSS2:ETS prostate cancer risk: results From the Prostate Cancer Prevention Trial. | Urology | 2014 Jul |
1 |
| 41 | 24926821 | The prostate cancer TMPRSS2:ERG fusion synergizes with the vitamin D receptor (VDR) to induce CYP24A1 expression-limiting VDR signaling. | Endocrinology | 2014 Sep |
8 |
| 42 | 25043536 | KLK3, PCA3, and TMPRSS2-ERG expression in the peripheral blood mononuclear cell fraction from castration-resistant prostate cancer patients and response to docetaxel treatment. | Prostate | 2014 Sep |
2 |
| 43 | 25088707 | Pyrrole-imidazole polyamide targeted to break fusion sites in TMPRSS2 and ERG gene fusion represses prostate tumor growth. | Cancer Sci | 2014 Oct |
2 |
| 44 | 25266362 | Antibody-independent targeted quantification of TMPRSS2-ERG fusion protein products in prostate cancer. | Mol Oncol | 2014 Oct |
1 |
| 45 | 25728532 | The TMPRSS2:ERG fusion and response to androgen deprivation therapy for prostate cancer. | Prostate | 2015 Jun 15 |
2 |
| 46 | 25933120 | Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer. | PLoS One | 2015 |
3 |
| 47 | 26095298 | Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics. | Eur J Cell Biol | 2015 Jul-Sep |
1 |
| 48 | 26503111 | Aspirin and NSAID use in association with molecular subtypes of prostate cancer defined by TMPRSS2:ERG fusion status. | Prostate Cancer Prostatic Dis | 2016 Mar |
1 |
| 49 | 26571387 | Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide. | PLoS One | 2015 |
2 |
| 50 | 26623558 | Integration of tissue metabolomics, transcriptomics and immunohistochemistry reveals ERG- and gleason score-specific metabolomic alterations in prostate cancer. | Oncotarget | 2016 Jan 12 |
1 |