mitogen-activated protein kinase 8 ; Homo sapiens






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1 7479845 Complexes of p21RAS with JUN N-terminal kinase and JUN proteins. Proc Natl Acad Sci U S A 1995 Nov 7 1
2 7535770 Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 1995 Mar 31 2
3 7565768 Angiotensin II stimulates calcium-dependent activation of c-Jun N-terminal kinase. Mol Cell Biol 1995 Nov 7
4 7593197 Integrin function: molecular hierarchies of cytoskeletal and signaling molecules. J Cell Biol 1995 Nov 2
5 7618106 Integration of MAP kinase signal transduction pathways at the serum response element. Science 1995 Jul 21 1
6 7629120 c-Jun N-terminal kinase but not mitogen-activated protein kinase is sensitive to cAMP inhibition in T lymphocytes. J Biol Chem 1995 Jul 28 5
7 7721728 Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP-1-dependent gene activation. J Biol Chem 1995 Apr 14 1
8 7824938 Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 1995 Jan 20 1
9 7929360 Tumor necrosis factor alpha stimulates AP-1 activity through prolonged activation of the c-Jun kinase. J Biol Chem 1994 Oct 21 1
10 8047888 An osmosensing signal transduction pathway in mammalian cells. Science 1994 Aug 5 2
11 8137421 JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 1994 Mar 25 4
12 8205621 JNK is involved in signal integration during costimulation of T lymphocytes. Cell 1994 Jun 3 2
13 8224842 Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev 1993 Nov 1
14 8530360 Cellular stresses differentially activate c-Jun N-terminal protein kinases and extracellular signal-regulated protein kinases in cultured ventricular myocytes. J Biol Chem 1995 Dec 15 1
15 8530447 c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-beta-D-arabinofuranosylcytosine. J Biol Chem 1995 Dec 22 1
16 8557665 Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis. J Biol Chem 1996 Jan 12 2
17 8607977 Transcriptional regulation by MAP kinases. Mol Reprod Dev 1995 Dec 6
18 8626428 SOS phosphorylation and disassociation of the Grb2-SOS complex by the ERK and JNK signaling pathways. J Biol Chem 1996 Mar 15 4
19 8645177 The differential regulation of cyclic AMP by sphingomyelin-derived lipids and the modulation of sphingolipid-stimulated extracellular signal regulated kinase-2 in airway smooth muscle. Biochem J 1996 May 1 6
20 8647130 Sphingomyelin-derived lipids differentially regulate the extracellular signal-regulated kinase 2 (ERK-2) and c-Jun N-terminal kinase (JNK) signal cascades in airway smooth muscle. Eur J Biochem 1996 May 1 9
21 8654373 Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO J 1996 Jun 3 2
22 8657285 Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature 1996 Jun 27 2
23 8663428 Galpha12 stimulates c-Jun NH2-terminal kinase through the small G proteins Ras and Rac. J Biol Chem 1996 Jul 19 1
24 8674048 Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1. Cancer Res 1996 Jul 1 14
25 8702674 Differential activation of mitogen-activated protein kinases by nitric oxide-related species. J Biol Chem 1996 Aug 16 3
26 8702835 Cyclic AMP inhibition of thrombin-induced growth in vascular smooth muscle cells correlates with decreased JNK1 activity and c-Jun expression. J Biol Chem 1996 Aug 23 2
27 8760286 Rac-1 dependent stimulation of the JNK/SAPK signaling pathway by Vav. Oncogene 1996 Aug 1 1
28 8780897 Impaired jun-NH2-terminal kinase activation by ultraviolet irradiation in fibroblasts of patients with Cockayne syndrome complementation group B. Cell Growth Differ 1996 Jun 1
29 8805275 Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway. Curr Biol 1996 May 1 2
30 8805335 p38/RK is essential for stress-induced nuclear responses: JNK/SAPKs and c-Jun/ATF-2 phosphorylation are insufficient. Curr Biol 1996 Aug 1 3
31 8824197 The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a Pak-independent signaling pathway. J Biol Chem 1996 Oct 18 2
32 8824287 JNK (c-Jun NH2-terminal kinase) is a target for antioxidants in T lymphocytes. J Biol Chem 1996 Oct 18 9
33 8831497 Ceramide is not a signal for tumor necrosis factor-induced gene expression but does cause programmed cell death in human vascular endothelial cells. Circ Res 1996 Oct 1
34 8875991 Phosphorylation-dependent targeting of c-Jun ubiquitination by Jun N-kinase. Oncogene 1996 Oct 3 2
35 8887624 The Ras-JNK pathway is involved in shear-induced gene expression. Mol Cell Biol 1996 Nov 1
36 8892112 Activation of C-jun N-terminal kinase/stress-activated protein kinase in primary glial cultures. J Neurosci Res 1996 Oct 1 4
37 8900190 The selective protein kinase C inhibitor, Ro-31-8220, inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) expression, induces c-Jun expression, and activates Jun N-terminal kinase. J Biol Chem 1996 Oct 25 2
38 8910292 Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family. J Biol Chem 1996 Nov 1 3
39 8913269 Adriamycin activates c-jun N-terminal kinase in human leukemia cells: a relevance to apoptosis. Cancer Lett 1996 Oct 1 2
40 8925912 SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases. FEBS Lett 1996 Apr 1 2
41 8939945 Activation of a novel calcium-dependent protein-tyrosine kinase. Correlation with c-Jun N-terminal kinase but not mitogen-activated protein kinase activation. J Biol Chem 1996 Nov 22 5
42 8940056 Jun N-terminal kinase mediates activation of skeletal muscle glycogen synthase by insulin in vivo. J Biol Chem 1996 Nov 29 1
43 8940082 Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs. J Biol Chem 1996 Nov 29 4
44 8943238 The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. J Biol Chem 1996 Dec 13 3
45 8950029 Effects of Ara-C on neutral sphingomyelinase and mitogen- and stress-activated protein kinases in T-lymphocyte cell lines. Biochem Mol Biol Int 1996 Nov 2
46 8950192 Initiation of acute phase response and synthesis of cytokines. Biochim Biophys Acta 1996 Nov 15 1
47 8967341 Interleukin-1 beta activates c-jun NH2-terminal kinase subgroup of mitogen-activated protein kinases in mesangial cells. Am J Physiol 1996 Apr 4
48 8972182 Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases. Mol Cell Biol 1997 Jan 1
49 8999940 Activation of 12-O-tetradecanoylphorbol-13-acetate response element- and dyad symmetry element-dependent transcription by interleukin-5 is mediated by Jun N-terminal kinase/stress-activated protein kinase kinases. J Biol Chem 1997 Jan 24 1
50 9020192 c-Jun NH2-terminal kinase-mediated activation of interleukin-1beta converting enzyme/CED-3-like protease during anticancer drug-induced apoptosis. J Biol Chem 1997 Feb 14 7