asoxime chloride






162 Article(s)
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1 668812 Successful oxime therapy one hour after soman intoxication in the rat. Eur J Pharmacol 1978 Jun 15 2
2 1412499 Studies of the amplification of carbaryl toxicity by various oximes. Toxicol Lett 1992 Sep 1
3 1459041 The effect of pyridostigmine pretreatment on oxime efficacy against intoxication by soman or VX in rats. Drug Chem Toxicol 1992 3
4 1631893 Therapeutic efficacy of HI-6 in soman-poisoned marmoset monkeys. Toxicol Appl Pharmacol 1992 Jul 4
5 1664202 Therapy of organophosphate poisoning in the rat by direct effects of oximes unrelated to ChE reactivation. Arch Toxicol 1991 2
6 1664331 On the mechanism whereby HI-6 improves neuromuscular function after oxime-resistant acetylcholinesterase inhibition and subsequent impairment of neuromuscular transmission. Eur J Pharmacol 1991 Aug 6 3
7 1675101 HI-6 in man: efficacy of the oxime in poisoning by organophosphorus insecticides. Hum Exp Toxicol 1991 Mar 1
8 1733041 Central activity of acetylcholinesterase oxime reactivators. Toxicol Appl Pharmacol 1992 Jan 2
9 1890690 Phosphylation kinetic constants and oxime-induced reactivation in acetylcholinesterase from fetal bovine serum, bovine caudate nucleus, and electric eel. J Toxicol Environ Health 1991 Sep 1
10 1987659 The synergism of atropine and the cholinesterase reactivator HI-6 in counteracting lethality by organophosphate intoxication in the rat. Toxicol Appl Pharmacol 1991 Jan 2
11 1998202 A comparison of cholinergic effects of HI-6 and pralidoxime-2-chloride (2-PAM) in soman poisoning. Toxicol Lett 1991 Feb 3
12 2046471 Evaluation of phosphinates as potential pretreatments for nerve agents. Life Sci 1991 2
13 2052186 The role of carboxylesterase in species variation of oxime protection against soman. Neurosci Biobehav Rev 1991 Spring 3
14 2059672 HI-6 and 2-PAM in sheep: pharmacokinetics and effects on muscle tissue following intramuscular injection. Biopharm Drug Dispos 1991 Apr 1
15 2494778 The relationship between oxime-induced reactivation of carbamylated acetylcholinesterase and antidotal efficacy against carbamate intoxication. Toxicol Appl Pharmacol 1989 Mar 15 2
16 2596267 Attenuation of soman-induced lesions of skeletal muscle by acetylcholinesterase reactivating and non-reactivating antidotes. Acta Neuropathol 1989 1
17 2742504 Mechanism of action of HI-6 on soman inhibition of acetylcholinesterase in preparations of rat and human skeletal muscle; comparison to SAD-128 and PAM-2. Arch Toxicol 1989 5
18 2917018 The bispyridinium-dioxime HLö-7. A potent reactivator for acetylcholinesterase inhibited by the stereoisomers of tabun and soman. Biochem Pharmacol 1989 Feb 15 1
19 3345199 Effects of some mono- and bisquaternary ammonium compounds on the reactivatability of soman-inhibited human acetylcholinesterase in vitro. Biochem Pharmacol 1988 Mar 1 1
20 3827594 Studies on the decomposition of the oxime HI 6 in aqueous solution. Arch Toxicol 1986 Dec 1
21 3951676 Effect of HI-6, applied into the cerebral ventricles, on the inhibition of brain acetylcholinesterase by soman in rats. Neuropharmacology 1986 Jan 7
22 4092883 Soman intoxication and the blood-brain barrier. Fundam Appl Toxicol 1985 Dec 1
23 6083633 Effects of HI-6 on brain neuronal RNA and acetylcholinesterase: metabolic responses during acute soman intoxication. Toxicology 1984 Dec 1
24 6327447 Isolation, in vitro activity, and acute toxicity in mice of the four stereoisomers of soman. Fundam Appl Toxicol 1984 Apr 1
25 6354300 [Trial of cholinesterase reactivators as proserine antagonists]. Biull Eksp Biol Med 1983 Oct 1
26 6547103 Effect of PAM-2 Cl, HI-6, and HGG-12 in poisoning by tabun and its thiocholine-like analog in the rat. Fundam Appl Toxicol 1984 Apr 1
27 6710485 Isolation, anticholinesterase properties, and acute toxicity in mice of the four stereoisomers of the nerve agent soman. Toxicol Appl Pharmacol 1984 Jan 1
28 6860351 Cholinesterase and carboxylesterase activities in soman poisoned rats treated with bispyridinium mono-oximes HI-6 and HS-6. Biochem Pharmacol 1983 May 15 1
29 6897946 Toxicology and pharmacology of bispyridium oximes--insight into the mechanism of action vs Soman poisoning in vivo. Fundam Appl Toxicol 1981 Mar-Apr 3
30 7092921 HI-6: reactivation of central and peripheral acetylcholinesterase following inhibition by soman, sarin and tabun in vivo in the rat. Biochem Pharmacol 1982 Apr 1 4
31 7184784 The treatment of Soman poisoning and its perspectives. Fundam Appl Toxicol 1981 Mar-Apr 1
32 7426043 Reactivation of acetylcholinesterase inhibited by 1,2,2'-trimethylpropyl methylphosphonofluoridate (soman) with HI-6 and related oximes. Biochem Pharmacol 1980 Sep 1 1
33 7495383 Interaction of phosphamidon with neuropathy target esterase and acetylcholinesterase of hen brain. Arch Toxicol 1995 1
34 7633327 Differential reactivation by HI-6 in vivo of paraoxon-inhibited rat brain acetylcholinesterase molecular forms. Neurochem Int 1995 Apr 1
35 7717860 Non-reactivating effects of HI-6 on hippocampal neurotransmission. Arch Toxicol 1994 1
36 7857205 In vitro oxime-induced reactivation of various molecular forms of soman-inhibited acetylcholinesterase in striated muscle from rat, monkey and human. Arch Toxicol 1994 4
37 7881866 Protein kinase C modulation of rhodanese-catalyzed conversion of cyanide to thiocyanate. Res Commun Mol Pathol Pharmacol 1994 Nov 4
38 8065529 The functional role of molecular forms of acetylcholinesterase in neuromuscular transmission. Neurochem Res 1994 Jun 1
39 8161944 Rate constants of carbamylation and decarbamylation of acetylcholinesterase for physostigmine and carbaryl in the presence of an oxime. Neurochem Int 1994 Feb 1
40 8304979 Amplification of the effectiveness of acetylcholinesterase for detoxification of organophosphorus compounds by bis-quaternary oximes. Biochem Pharmacol 1994 Jan 20 2
41 8311691 Comparison of several oximes on reactivation of soman-inhibited blood, brain and tissue cholinesterase activity in rats. Arch Toxicol 1993 8
42 8343986 Cholinesterases as scavengers for organophosphorus compounds: protection of primate performance against soman toxicity. Chem Biol Interact 1993 Jun 1
43 8382066 The influence of soman simulator on reactivation by HI-6 of soman-inhibited acetylcholinesterase in preparations of rat and human skeletal muscle. Biochem Pharmacol 1993 Jan 26 2
44 8441737 Efficacy of antidotes against soman poisoning in female physostigmine-protected rats. Pharmacol Toxicol 1993 Jan 2
45 8493783 [Pharmacokinetics of the oxime, HI-6, in patients with acute organophosphorus insecticide poisoning]. Vojnosanit Pregl 1993 Jan-Feb 1
46 8603667 Genetic toxicology assessment of HI-6 dichloride. Environ Mol Mutagen 1996 2
47 8750900 Methantheline improves the reactivation by HI 6 of human erythrocyte acetylcholinesterase inhibited by soman in vitro. Arch Toxicol 1995 2
48 8911635 Pharmacological effects of oximes: how relevant are they? Arch Toxicol 1996 1
49 9271331 Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning. Biochem Pharmacol 1997 Jul 15 7
50 9298924 Pharmacokinetics and effects of HI 6 in blood and brain of soman-intoxicated rats: a microdialysis study. Eur J Pharmacol 1997 Jul 30 1