Probucol






228 Article(s)
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51 8774625 Effectiveness of probucol in preventing restenosis after percutaneous transluminal coronary angioplasty. Jpn Heart J 1996 May 1
52 8855936 Selective inhibition of free apolipoprotein-mediated cellular lipid efflux by probucol. Biochemistry 1996 Oct 8 2
53 8937690 RT-PCR study on the effects of minimally modified low-density lipoproteins and probucol treatment on gene expressions of interleukin-1 and platelet-derived growth factor B-chain in human peripheral blood mononuclear cells. Biol Signals 1996 Sep-Oct 1
54 8958136 Antioxidants inhibit the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 induced by oxidized LDL on human umbilical vein endothelial cells. Free Radic Biol Med 1997 2
55 9096917 Efficacy and safety of the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin in hyperlipidemic patients treated with probucol. Cardiology 1997 Mar-Apr 2
56 9185508 Paradoxical enhancement of atherosclerosis by probucol treatment in apolipoprotein E-deficient mice. J Clin Invest 1997 Jun 15 3
57 9222645 Oxidized lipoproteins found in patients with NIDDM stimulate radical-induced monocyte chemoattractant protein-1 mRNA expression in cultured human endothelial cells. Diabetologia 1997 Jun 2
58 9469511 Effect of probucol on serum lipoprotein and apoprotein profiles in renal transplant patients. Am J Kidney Dis 1998 Feb 3
59 9497899 Role of superoxide anions in changes of endothelial vasoactive response during acute hyperglycemia. Horm Metab Res 1997 Dec 1
60 9503394 [Effect of F-1394, a potent and selective inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), on esterification of cholesterol and basolateral secretion of cholesteryl ester in Caco-2 cells]. Nihon Yakurigaku Zasshi 1997 Dec 1
61 9714785 Mechanism of action of probucol on cholesteryl ester transfer protein (CETP) mRNA in a Chinese hamster ovary cell line that had been stably transfected with a human CETP gene. Biochim Biophys Acta 1998 Jul 31 1
62 9784904 Effect of probucol on smooth muscle cell proliferation and dedifferentiation after vascular injury in rabbits: possible role of PDGF. Cardiovasc Drugs Ther 1998 Jul 1
63 9832328 Probucol inhibits oxidized-low density lipoprotein-induced adhesion of monocytes to endothelial cells by reducing P-selectin synthesis in vitro. Endothelium 1998 6
64 9880814 Facile degradation of apolipoprotein B by radical reactions and the presence of cleaved proteins in serum. J Biochem 1999 Jan 1
65 10077523 Antioxidants improve impaired insulin-mediated glucose uptake and prevent migration and proliferation of cultured rabbit coronary smooth muscle cells induced by high glucose. Circulation 1999 Mar 16 1
66 10323786 Probucol enhances selective uptake of HDL-associated cholesteryl esters in vitro by a scavenger receptor B-I-dependent mechanism. Arterioscler Thromb Vasc Biol 1999 May 2
67 10412769 Involvement of MCP-1 and M-CSF in glomerular foam cell formation in ExHC rats. Kidney Int Suppl 1999 Jul 1
68 10488970 Opposite effects on serum cholesteryl ester transfer protein levels between long-term treatments with pravastatin and probucol in patients with primary hypercholesterolemia and xanthoma. Atherosclerosis 1999 Aug 4
69 10638221 [Mechanisms of anti-atherogenic action of probucol]. Nihon Rinsho 1999 Dec 1
70 10728389 Antioxidants attenuate myocyte apoptosis in the remote non-infarcted myocardium following large myocardial infarction. Cardiovasc Res 2000 Feb 4
71 10962201 Induction of aldose reductase in cultured human microvascular endothelial cells by advanced glycation end products. Free Radic Biol Med 2000 Jul 1 1
72 10998462 Effects of probucol on cholesterol metabolism in mouse peritoneal macrophages: inhibition of HDL-mediated cholesterol efflux. Atherosclerosis 2000 Oct 8
73 10998472 Probucol promotes reverse cholesterol transport in heterozygous familial hypercholesterolemia. Effects on apolipoprotein AI-containing lipoprotein particles. Atherosclerosis 2000 Oct 1
74 11044428 Adriamycin-induced early changes in myocardial antioxidant enzymes and their modulation by probucol. Circulation 2000 Oct 24 1
75 11132040 Pathogenetic concepts of membranous glomerulopathy (MGN). J Nephrol 2000 Nov-Dec 1
76 11291592 Apoptosis in adriamycin cardiomyopathy and its modulation by probucol. Antioxid Redox Signal 2001 Feb 1
77 11398149 Hepatic cholesterol and bile acid synthesis, low-density lipoprotein receptor function, and plasma and fecal sterol levels in mice: effects of apolipoprotein E deficiency and probucol or phytosterol treatment. Metabolism 2001 Jun 1
78 11463759 Endothelial apoptosis induced by oxidative stress through activation of NF-kappaB: antiapoptotic effect of antioxidant agents on endothelial cells. Hypertension 2001 Jul 2
79 11533053 Anti-atherogenic antioxidants regulate the expression and function of proteasome alpha-type subunits in human endothelial cells. J Biol Chem 2001 Nov 2 1
80 11544561 Effects of probucol on atherosclerosis of apoE-deficient or LDL receptor-deficient mice. Horm Metab Res 2001 Aug 9
81 11814474 Comparison of antioxidant effects of naringin and probucol in cholesterol-fed rabbits. Clin Chim Acta 2002 Mar 2
82 12007724 Probucol preserves pancreatic beta-cell function through reduction of oxidative stress in type 2 diabetes. Diabetes Res Clin Pract 2002 Jul 1
83 12014681 Probucol and liver efficiency during chemically-induced hepatocarcinogenesis. Anticancer Res 2002 Mar-Apr 1
84 12060525 Probucol inhibits oxidized-low density lipoprotein-induced adhesion of monocytes to endothelial cells in vitro. Acta Pharmacol Sin 2002 Jun 4
85 12065220 DNA damage and the effect of antioxidants in streptozotocin-treated mice. Food Chem Toxicol 2002 Jul 2
86 12215472 Mitogenic activity of oxidized lipoprotein (a) on human vascular smooth muscle cells. Hypertension 2002 Sep 2
87 12435748 Apoptotic neuronal cell death induced by the non-fibrillar amyloid-beta peptide proceeds through an early reactive oxygen species-dependent cytoskeleton perturbation. J Biol Chem 2003 Jan 31 1
88 12646204 NF-kappa B activation in endothelial cells treated with oxidized high-density lipoprotein. Biochem Biophys Res Commun 2003 Mar 28 2
89 12818576 NADPH oxidase-derived superoxide anion mediates angiotensin II-induced cardiac hypertrophy. J Mol Cell Cardiol 2003 Jul 3
90 12874441 Effects of antioxidants in diabetes-induced oxidative stress in the glomeruli of diabetic rats. J Am Soc Nephrol 2003 Aug 1
91 12946703 The cholesterol-lowering drug probucol increases apolipoprotein E production in the hippocampus of aged rats: implications for Alzheimer's disease. Neuroscience 2003 11
92 14519959 Probucol decreases mevalonate pyrophosphate decarboxylase in the rat liver. Biol Pharm Bull 2003 Oct 4
93 14562608 Protective effects of probucol treatment on pancreatic beta-cell function of SZ-induced diabetic APA hamsters. Exp Anim 2003 Jul 11
94 14617690 Selective inhibition of endothelial and monocyte redox-sensitive genes by AGI-1067: a novel antioxidant and anti-inflammatory agent. J Pharmacol Exp Ther 2004 Mar 1
95 14642415 Modulation of HDL metabolism by probucol in complete cholesteryl ester transfer protein deficiency. Atherosclerosis 2003 Nov 2
96 14644392 Cytotoxic cellular cholesterol is selectively removed by apoA-I via ABCA1. Atherosclerosis 2003 Dec 1
97 14701812 Depletion of pre-beta-high density lipoprotein by human chymase impairs ATP-binding cassette transporter A1- but not scavenger receptor class B type I-mediated lipid efflux to high density lipoprotein. J Biol Chem 2004 Mar 12 2
98 15182357 Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages and increases lipid accumulation in the cells. Eur J Biochem 2004 Jun 3
99 15338110 3,4,5,6-Tetrahydroxyxanthone prevents vascular endothelial cell apoptosis induced by high glucose. Naunyn Schmiedebergs Arch Pharmacol 2004 Oct 1
100 15364806 Probucol protects against smooth muscle cell proliferation by upregulating heme oxygenase-1. Circulation 2004 Sep 28 1