2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid






148 Article(s)
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1 9808856 Fibroblasts cultured from venous ulcers display cellular characteristics of senescence. J Vasc Surg 1998 Nov 1
2 10372905 Cellular senescence of angiofibroma stroma cells from patients with tuberous sclerosis. Brain Dev 1999 Apr 1
3 11344338 MK/T-1, an immortalized fibroblast cell line derived using cultures of mouse corneal stroma. Mol Vis 2001 May 8 1
4 14504464 ERM proteins and Cdk5 in cellular senescence. Cell Cycle 2003 Nov-Dec 1
5 14580871 TGF-beta cytokines increase senescence-associated beta-galactosidase activity in human prostate basal cells by supporting differentiation processes, but not cellular senescence. Exp Gerontol 2003 Oct 2
6 15162381 Interleukin-8 expression is increased in senescent prostatic epithelial cells and promotes the development of benign prostatic hyperplasia. Prostate 2004 Jul 1 1
7 15753076 The ATM/p53/p21 pathway influences cell fate decision between apoptosis and senescence in reoxygenated hematopoietic progenitor cells. J Biol Chem 2005 May 20 4
8 16107615 p63 deficiency activates a program of cellular senescence and leads to accelerated aging. Genes Dev 2005 Sep 1 1
9 16380648 ECRG1, a novel candidate of tumor suppressor gene in the esophageal carcinoma, triggers a senescent program in NIH3T3 cells. Exp Biol Med (Maywood) 2006 Jan 1
10 16615275 Enhanced expression of halp gene confers cellular resistance to H2O2 induced senescence. Chin Med Sci J 2006 Mar 1
11 16626397 Senescence-associated beta-galactosidase is lysosomal beta-galactosidase. Aging Cell 2006 Apr 6
12 16731828 Apoptosis signal-regulating kinase 1 mediates cellular senescence induced by high glucose in endothelial cells. Diabetes 2006 Jun 1
13 16818621 Coexpression of NRASQ61R and BRAFV600E in human melanoma cells activates senescence and increases susceptibility to cell-mediated cytotoxicity. Cancer Res 2006 Jul 1 1
14 17050172 Inhibitory effect of peroxiredoxin II (Prx II) on Ras-ERK-NFkappaB pathway in mouse embryonic fibroblast (MEF) senescence. Free Radic Res 2006 Nov 1
15 17297436 Accelerated senescence of human peritoneal mesothelial cells exposed to high glucose: the role of TGF-beta1. Lab Invest 2007 Apr 2
16 17432596 [Role of p38alpha kinase in activation of premature senescence program in transformed mouse fibroblasts]. Tsitologiia 2007 1
17 17447021 Effect of cell cycle inhibitor p19ARF on senescence of human diploid cell. Sci China C Life Sci 2007 Apr 1
18 17560572 Normal or stress-induced fibroblast senescence involves COX-2 activity. Exp Cell Res 2007 Aug 15 1
19 17634571 Methods to detect biomarkers of cellular senescence: the senescence-associated beta-galactosidase assay. Methods Mol Biol 2007 1
20 17635417 Regulation of replicative senescence by insulin-like growth factor-binding protein 3 in human umbilical vein endothelial cells. Aging Cell 2007 Aug 2
21 17916362 Sirt1 modulates premature senescence-like phenotype in human endothelial cells. J Mol Cell Cardiol 2007 Nov 2
22 18313665 Multiple effects of TRAIL in human carcinoma cells: induction of apoptosis, senescence, proliferation, and cytokine production. Exp Cell Res 2008 Apr 15 1
23 19048622 p53 dependent cell-cycle arrest triggered by chemotherapy in xenografted breast tumors. Int J Cancer 2009 Feb 15 1
24 19071156 Interferon-gamma induces cellular senescence through p53-dependent DNA damage signaling in human endothelial cells. Mech Ageing Dev 2009 Mar 1
25 19364500 UV light induces premature senescence in Akt1-null mouse embryonic fibroblasts by increasing intracellular levels of ROS. Biochem Biophys Res Commun 2009 Jun 5 3
26 19492297 Downregulation of APE1/Ref-1 is involved in the senescence of mesenchymal stem cells. Stem Cells 2009 Jun 2
27 19799355 [Effect of histone deacetylases inhibitor sodium butyrate (NaB) on transformants E1A + cHa-Ras expressing wild type p53 with supressed transactivation function]. Tsitologiia 2009 1
28 20103533 Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1. J Cell Sci 2010 Feb 15 4
29 20453494 Angiopoietin-1 inhibits mouse glomerular endothelial cell senescence via Tie2 receptor-modulated ERK1/2 signaling. Am J Nephrol 2010 1
30 20457127 Senescence-associated beta-galactosidase activity expression in aging hippocampal neurons. Biochem Biophys Res Commun 2010 Jun 11 2
31 20554622 TGF-{beta}2 induces senescence-associated changes in human trabecular meshwork cells. Invest Ophthalmol Vis Sci 2010 Nov 1
32 20647331 p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase. Mol Cancer Res 2010 Aug 5
33 21132465 Establishment of an aging model of Sca-1+ hematopoietic stem cell and studies on its relative biological mechanisms. In Vitro Cell Dev Biol Anim 2011 Feb 1
34 21423768 Epstein-Barr virus (EBV) Rta-mediated EBV and Kaposi's sarcoma-associated herpesvirus lytic reactivations in 293 cells. PLoS One 2011 Mar 10 1
35 21657082 [Experimental study of relationship between effect of ginsenoside Rg1 to delay hematopoietic stem cell senescence and expression of p16(INK4a)]. Zhongguo Zhong Yao Za Zhi 2011 Mar 1
36 21872575 AMPK induces vascular smooth muscle cell senescence via LKB1 dependent pathway. Biochem Biophys Res Commun 2011 Sep 16 2
37 21967847 The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression. Nucleic Acids Res 2012 Feb 1
38 22030897 Ginsenoside Rb1 reverses H2O2-induced senescence in human umbilical endothelial cells: involvement of eNOS pathway. J Cardiovasc Pharmacol 2012 Mar 1
39 22090360 TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence. Clin Cancer Res 2012 Jan 1 1
40 22633096 Accelerated senescence of renal tubular epithelial cells is associated with disease progression of patients with immunoglobulin A (IgA) nephropathy. Transl Res 2012 Jun 1
41 22877754 IGF-I enhances cellular senescence via the reactive oxygen species-p53 pathway. Biochem Biophys Res Commun 2012 Aug 24 1
42 22898871 Apoptosis and autophagy have opposite roles on imatinib-induced K562 leukemia cell senescence. Cell Death Dis 2012 Aug 16 3
43 23430755 Bexarotene induces cellular senescence in MMTV-Neu mouse model of mammary carcinogenesis. Cancer Prev Res (Phila) 2013 Apr 1
44 23494737 SIRT3 overexpression antagonizes high glucose accelerated cellular senescence in human diploid fibroblasts via the SIRT3-FOXO1 signaling pathway. Age (Dordr) 2013 Dec 1
45 23727633 Glucocorticoids induce senescence in primary human tenocytes by inhibition of sirtuin 1 and activation of the p53/p21 pathway: in vivo and in vitro evidence. Ann Rheum Dis 2014 Jul 1
46 23935871 The transcriptional cofactor MCAF1/ATF7IP is involved in histone gene expression and cellular senescence. PLoS One 2013 1
47 23982736 Low concentration of metformin induces a p53-dependent senescence in hepatoma cells via activation of the AMPK pathway. Int J Oncol 2013 Nov 1
48 24094550 Regulation of ROS-independent ERK signaling rescues replicative cellular senescence in ex vivo expanded human c-kit-positive cardiac progenitor cells. Int J Cardiol 2013 Oct 25 2
49 24113348 Receptor for advanced glycation end-products promotes premature senescence of proximal tubular epithelial cells via activation of endoplasmic reticulum stress-dependent p21 signaling. Cell Signal 2014 Jan 3
50 24205274 Inhibition of IGF-1R prevents ionizing radiation-induced primary endothelial cell senescence. PLoS One 2013 1