| 1 | 10463616 | Inhibition of bladder carcinoma angiogenesis, stromal support, and tumor growth by halofuginone. | Cancer Res | 1999 Aug 15 |
1 |
| 2 | 10473075 | Inhibition of matrix metalloproteinase-2 expression and bladder carcinoma metastasis by halofuginone. | Clin Cancer Res | 1999 Aug |
6 |
| 3 | 10772506 | Use of epidermal growth factor and collagen synthesis inhibition as adjuvant to healing of ureteroureteral anastomosis. | J Endourol | 2000 Mar |
1 |
| 4 | 11099465 | Halofuginone: a potent inhibitor of critical steps in angiogenesis progression. | FASEB J | 2000 Dec |
5 |
| 5 | 11705455 | Reduction in dermal fibrosis in the tight-skin (Tsk) mouse after local application of halofuginone. | Biochem Pharmacol | 2001 Nov 1 |
4 |
| 6 | 11874485 | Halofuginone, an inhibitor of type-I collagen synthesis and skin sclerosis, blocks transforming-growth-factor-beta-mediated Smad3 activation in fibroblasts. | J Invest Dermatol | 2002 Mar |
5 |
| 7 | 12384935 | Halofuginone inhibition of COL1A2 promoter activity via a c-Jun-dependent mechanism. | Arthritis Rheum | 2002 Oct |
15 |
| 8 | 12482197 | Effect of halofuginone on the development of tight skin (TSK) syndrome. | Autoimmunity | 2002 Jul |
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| 9 | 12869955 | Halofuginone to treat fibrosis in chronic graft-versus-host disease and scleroderma. | Biol Blood Marrow Transplant | 2003 Jul |
2 |
| 10 | 14506172 | Treatment with halofuginone results in marked growth inhibition of a von Hippel-Lindau pheochromocytoma in vivo. | Clin Cancer Res | 2003 Sep 1 |
2 |
| 11 | 14732719 | Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone. | J Biol Chem | 2004 Apr 9 |
10 |
| 12 | 15154911 | Smad3 as a mediator of the fibrotic response. | Int J Exp Pathol | 2004 Apr |
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| 13 | 15177499 | Suppression of hepatocellular carcinoma growth in mice by the alkaloid coccidiostat halofuginone. | Eur J Cancer | 2004 Jun |
5 |
| 14 | 16148645 | Inhibition of Wilms tumor xenograft progression by halofuginone is accompanied by activation of WT-1 gene expression. | J Urol | 2005 Oct |
4 |
| 15 | 16418571 | Halofuginone inhibits tumor growth in the polyoma middle T antigen mouse via a thrombospondin-1 independent mechanism. | Cancer Biol Ther | 2006 Feb |
11 |
| 16 | 16489207 | Halofuginone induces matrix metalloproteinases in rat hepatic stellate cells via activation of p38 and NFkappaB. | J Biol Chem | 2006 Jun 2 |
11 |
| 17 | 16508789 | Involvement of the tyrosine phosphatase early gene of liver regeneration (PRL-1) in cell cycle and in liver regeneration and fibrosis effect of halofuginone. | Cell Tissue Res | 2006 Jun |
11 |
| 18 | 16735800 | Inhibition of rat renal fibroblast proliferation by halofuginone. | Nephron Exp Nephrol | 2006 |
4 |
| 19 | 16756723 | Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition. | Neoplasia | 2006 Apr |
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| 20 | 16769768 | Halofuginone inhibits NF-kappaB and p38 MAPK in activated T cells. | J Leukoc Biol | 2006 Aug |
6 |
| 21 | 17180598 | Gene expression during chemically induced liver fibrosis: effect of halofuginone on TGF-beta signaling. | Cell Tissue Res | 2007 Apr |
6 |
| 22 | 17267660 | Inhibition of fibroblast to myofibroblast transition by halofuginone contributes to the chemotherapy-mediated antitumoral effect. | Mol Cancer Ther | 2007 Feb |
4 |
| 23 | 18458672 | Halofuginone upregulates the expression of heparanase in thioacetamide-induced liver fibrosis in rats. | Lab Invest | 2008 Jun |
3 |
| 24 | 18672370 | Prevention of muscle fibrosis and improvement in muscle performance in the mdx mouse by halofuginone. | Neuromuscul Disord | 2008 Nov |
3 |
| 25 | 18714394 | Myofibroblasts in pulmonary and brain metastases of alveolar soft-part sarcoma: a novel target for treatment? | Neoplasia | 2008 Sep |
3 |
| 26 | 19114027 | Halofuginone prevents extracellular matrix deposition in diabetic nephropathy. | Biochem Biophys Res Commun | 2009 Feb 6 |
6 |
| 27 | 19135664 | The antifibrotic drug halofuginone inhibits proliferation and collagen production by human leiomyoma and myometrial smooth muscle cells. | Fertil Steril | 2010 Mar 1 |
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| 28 | 19188864 | Inhibition of transforming growth factor beta signaling by halofuginone as a modality for pancreas fibrosis prevention. | Pancreas | 2009 May |
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| 29 | 19578745 | Halofuginone mediated protection against radiation-induced leg contracture. | Int J Oncol | 2009 Aug |
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| 30 | 19713035 | Halofuginone enhances the radiation sensitivity of human tumor cell lines. | Cancer Lett | 2010 Mar 1 |
2 |
| 31 | 19793022 | Halofuginone has a beneficial effect on gentamicin-induced acute nephrotoxicity in rats. | Drug Chem Toxicol | 2009 |
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| 32 | 20060825 | Halofuginone inhibits Smad3 phosphorylation via the PI3K/Akt and MAPK/ERK pathways in muscle cells: effect on myotube fusion. | Exp Cell Res | 2010 Apr 1 |
24 |
| 33 | 20442678 | Inhibition of pancreatic stellate cell activation by halofuginone prevents pancreatic xenograft tumor development. | Pancreas | 2010 Oct |
2 |
| 34 | 20944000 | IDO upregulates regulatory T cells via tryptophan catabolite and suppresses encephalitogenic T cell responses in experimental autoimmune encephalomyelitis. | J Immunol | 2010 Nov 15 |
3 |
| 35 | 21068672 | Phase II AIDS Malignancy Consortium trial of topical halofuginone in AIDS-related Kaposi sarcoma. | J Acquir Immune Defic Syndr | 2011 Jan 1 |
1 |
| 36 | 21078281 | Light-chain shuffling from an antigen-biased phage pool allows 185-fold improvement of an anti-halofuginone single-chain variable fragment. | Anal Biochem | 2011 Mar 1 |
6 |
| 37 | 21117034 | Halofuginone and muscular dystrophy. | Histol Histopathol | 2011 Jan |
4 |
| 38 | 22053203 | Halofuginone has anti-proliferative effects in acute promyelocytic leukemia by modulating the transforming growth factor beta signaling pathway. | PLoS One | 2011 |
3 |
| 39 | 22373656 | The antifibrotic drug halofuginone reduces ischemia/reperfusion-induced oxidative renal damage in rats. | J Pediatr Urol | 2013 Apr |
1 |
| 40 | 22393274 | Halofuginone down-regulates Smad3 expression and inhibits the TGFbeta-induced expression of fibrotic markers in human corneal fibroblasts. | Mol Vis | 2012 |
6 |
| 41 | 22848627 | Involvement of host stroma cells and tissue fibrosis in pancreatic tumor development in transgenic mice. | PLoS One | 2012 |
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| 42 | 22885662 | Inhibition of matrix metalloproteinase-2 by halofuginone is mediated by the Egr1 transcription factor. | Anticancer Drugs | 2012 Nov |
10 |
| 43 | 22971531 | Halofugine prevents cutaneous graft versus host disease by suppression of Th17 differentiation. | Hematology | 2012 Sep |
2 |
| 44 | 23002206 | Halofuginone inhibits the establishment and progression of melanoma bone metastases. | Cancer Res | 2012 Dec 1 |
13 |
| 45 | 23274062 | The involvement of collagen triple helix repeat containing 1 in muscular dystrophies. | Am J Pathol | 2013 Mar |
2 |
| 46 | 23275304 | Inhibition of muscle fibrosis and improvement of muscle histopathology in dysferlin knock-out mice treated with halofuginone. | Histol Histopathol | 2013 Feb |
4 |
| 47 | 23480137 | Targeting TGFβ signaling to inhibit fibroblast activation as a therapy for fibrosis and cancer: effect of halofuginone. | Expert Opin Drug Discov | 2008 Jan |
1 |
| 48 | 23845969 | Halofuginone down-regulates Smad3 expression and inhibits the TGFbeta-induced expression of fibrotic markers in human corneal fibroblasts. | Ann Plast Surg | 2014 Apr |
2 |
| 49 | 24100331 | Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone. | Acta Crystallogr D Biol Crystallogr | 2013 Oct |
3 |
| 50 | 24173318 | Halofuginone induces the apoptosis of breast cancer cells and inhibits migration via downregulation of matrix metalloproteinase-9. | Int J Oncol | 2014 Jan |
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