RTKI cpd






953 Article(s)
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1 7525285 Epidermal-growth-factor-dependent activation of the src-family kinases. Eur J Biochem 1994 Nov 1 2
2 7559780 Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition. J Cell Biol 1995 Oct 7
3 8752145 Tyrphostin AG 1478 preferentially inhibits human glioma cells expressing truncated rather than wild-type epidermal growth factor receptors. Cancer Res 1996 Sep 1 2
4 9138097 Opposing effects of tyrosine kinase inhibitors on mineralization of normal and tumor bone cells. J Cell Biochem 1997 Jun 1 2
5 9237626 Tyrphostin AG 494 blocks Cdk2 activation. FEBS Lett 1997 Jun 30 2
6 9288782 Inhibitors of epidermal growth factor receptor kinase and of cyclin-dependent kinase 2 activation induce growth arrest, differentiation, and apoptosis of human papilloma virus 16-immortalized human keratinocytes. Cancer Res 1997 Sep 1 3
7 9355759 Rapid stimulation of amyloid precursor protein release by epidermal growth factor: role of protein kinase C. Biochem J 1997 Oct 1 1
8 9416416 Inhibition of transforming growth factor alpha stimulation of human squamous cell carcinoma of the head and neck with anti-TGF-alpha antibodies and tyrphostin. Ann Surg Oncol 1997 Dec 2
9 9452417 Decorin activates the epidermal growth factor receptor and elevates cytosolic Ca2+ in A431 carcinoma cells. J Biol Chem 1998 Feb 6 1
10 9535870 Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells. J Biol Chem 1998 Apr 10 2
11 9563005 Preferential inhibition of glioblastoma cells with wild-type epidermal growth factor receptors by a novel tyrosine kinase inhibitor ethyl-2,5-dihydroxycinnamate. Oncol Res 1997 2
12 9595433 Endothelin-1 stimulates DNA synthesis of vascular smooth-muscle cells through transactivation of epidermal growth factor receptor. J Cardiovasc Pharmacol 1998 2
13 9710602 Tumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc. Mol Cell Biol 1998 Sep 1
14 9722539 Related adhesion focal tyrosine kinase and the epidermal growth factor receptor mediate the stimulation of mitogen-activated protein kinase by the G-protein-coupled P2Y2 receptor. Phorbol ester or [Ca2+]i elevation can substitute for receptor activation. J Biol Chem 1998 Sep 4 4
15 9736460 Opposing effects of cyclosporin A and tyrphostin AG-1478 indicate a role for Src protein in the cellular control of mineralization. J Cell Biochem 1998 Oct 1 2
16 9765228 Carbachol stimulates transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T84 cells. Implications for carbachol-stimulated chloride secretion. J Biol Chem 1998 Oct 16 3
17 9766567 STAT3 mediates the survival signal in oncogenic ras-transfected intestinal epithelial cells. Int J Cancer 1998 Oct 29 2
18 9856979 Arachidonate-induced tyrosine phosphorylation of epidermal growth factor receptor and Shc-Grb2-Sos association. Hypertension 1998 Dec 1
19 9869605 Gastrin induces heparin-binding epidermal growth factor-like growth factor in rat gastric epithelial cells transfected with gastrin receptor. Gastroenterology 1999 Jan 1
20 10092515 Chronic ethanol consumption disrupts complexation between EGF receptor and phospholipase C-gamma1: relevance to impaired hepatocyte proliferation. Biochem Biophys Res Commun 1999 Apr 2 5
21 10101228 ERK MAP kinase activation is required for acetylcholine receptor inducing activity-induced increase in all five acetylcholine receptor subunit mRNAs as well as synapse-specific expression of acetylcholine receptor epsilon-transgene. Brain Res Mol Brain Res 1999 Apr 6 2
22 10207024 The beta3-adrenergic receptor activates mitogen-activated protein kinase in adipocytes through a Gi-dependent mechanism. J Biol Chem 1999 Apr 23 2
23 10226546 Enhancement of chemosensitivity and programmed cell death by tyrosine kinase inhibitors correlates with EGFR expression in non-small cell lung cancer cells. Anticancer Res 1999 Jan-Feb 2
24 10381396 4-hydroxynonenal triggers an epidermal growth factor receptor-linked signal pathway for growth inhibition. J Cell Sci 1999 Jul 2
25 10393853 Specific inhibitors of platelet-derived growth factor or epidermal growth factor receptor tyrosine kinase reduce pulmonary fibrosis in rats. Am J Pathol 1999 Jul 1
26 10394957 Inhibition of epidermal-growth-factor-receptor-dependent signalling by tyrphostins A25 and AG1478 blocks growth and induces apoptosis in colorectal tumor cells in vitro. J Cancer Res Clin Oncol 1999 Jul 2
27 10440105 Epidermal growth factor receptor is indispensable for c-Fos expression and protein synthesis by angiotensin II. Eur J Pharmacol 1999 Jul 2 3
28 10446212 Nitric oxide inhibits angiotensin II-induced activation of the calcium-sensitive tyrosine kinase proline-rich tyrosine kinase 2 without affecting epidermal growth factor receptor transactivation. J Biol Chem 1999 Aug 20 3
29 10499523 Endothelin-mediated vascular growth requires p42/p44 mitogen-activated protein kinase and p70 S6 kinase cascades via transactivation of epidermal growth factor receptor. Endocrinology 1999 Oct 5
30 10516208 Asbestos-induced phosphorylation of epidermal growth factor receptor is linked to c-fos and apoptosis. Am J Physiol 1999 Oct 1
31 10533979 Ionizing radiation stimulates existing signal transduction pathways involving the activation of epidermal growth factor receptor and ERBB-3, and changes of intracellular calcium in A431 human squamous carcinoma cells. J Recept Signal Transduct Res 1999 Nov 5
32 10550326 Complement C5b-9 induces receptor tyrosine kinase transactivation in glomerular epithelial cells. Am J Pathol 1999 Nov 1
33 10559139 Regulation of sarcolemmal Na(+)/H(+) exchanger activity by angiotensin II in adult rat ventricular myocytes: opposing actions via AT(1) versus AT(2) receptors. Circ Res 1999 Nov 12 1
34 10565840 Mechanisms of 5-hydroxytryptamine(2A) receptor activation of the mitogen-activated protein kinase pathway in vascular smooth muscle. J Pharmacol Exp Ther 1999 Dec 1
35 10585878 Activation of tyrosine kinases by alpha1A-adrenergic and growth factor receptors in transfected PC12 cells. Biochem J 1999 Dec 15 2
36 10597250 LOT1 is a growth suppressor gene down-regulated by the epidermal growth factor receptor ligands and encodes a nuclear zinc-finger protein. Oncogene 1999 Nov 11 1
37 10601546 Auto-induction and growth stimulatory effect of betacellulin in human pancreatic cancer cells. Int J Oncol 2000 Jan 1
38 10640773 Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: role of neutrophils. J Immunol 2000 Feb 1 1
39 10653972 Fluid flow-induced tyrosine phosphorylation and participation of growth factor signaling pathway in osteoblast-like cells. J Cell Biochem 2000 Jan 4
40 10666084 Mechanical stretch stimulates growth of vascular smooth muscle cells via epidermal growth factor receptor. Am J Physiol Heart Circ Physiol 2000 Feb 2
41 10688043 Mitogenic signaling in androgen sensitive and insensitive prostate cancer cell lines. J Urol 2000 Mar 2
42 10702246 Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells. J Biol Chem 2000 Mar 10 3
43 10702262 Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity. J Biol Chem 2000 Mar 10 3
44 10766308 The human papillomavirus type 16 E5 protein modulates ERK1/2 and p38 MAP kinase activation by an EGFR-independent process in stressed human keratinocytes. Virus Genes 2000 1
45 10766863 Epidermal growth factor receptor tyrosine kinase mediates Ras activation by gonadotropin-releasing hormone. J Biol Chem 2000 Apr 21 5
46 10775424 Peroxynitrite modulates the activation of p38 and extracellular regulated kinases in PC12 cells. Arch Biochem Biophys 2000 Apr 15 2
47 10777220 Role of basal calcium in the EGF activation of MAP kinases. Oncogene 2000 Mar 30 2
48 10779380 Activation of signal transducers and activators of transcription by alpha(1A)-adrenergic receptor stimulation in PC12 cells. Mol Pharmacol 2000 May 1
49 10783131 Mechanism of extracellular signal-regulated kinase (ERK)-1 and ERK-2 activation by vanadium pentoxide in rat pulmonary myofibroblasts. Am J Respir Cell Mol Biol 2000 May 3
50 10801894 Peroxynitrite targets the epidermal growth factor receptor, Raf-1, and MEK independently to activate MAPK. J Biol Chem 2000 Jul 21 2