51 | 11284449 | P-glycoprotein-mediated transport of digitoxin, alpha-methyldigoxin and beta-acetyldigoxin. | Naunyn Schmiedebergs Arch Pharmacol | 2001 Mar |
2 |
52 | 11309248 | Direct inhibitory effect of digitalis on progesterone release from rat granulosa cells. | Br J Pharmacol | 2001 Apr |
8 |
53 | 11586264 | Inhibitory effects of digitalis on the proliferation of androgen dependent and independent prostate cancer cells. | J Urol | 2001 Nov |
1 |
54 | 12112021 | Progesterone attenuates the inhibitory effects of cardiotonic digitalis on pregnenolone production in rat luteal cells. | J Cell Biochem | 2002 |
4 |
55 | 15136726 | Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells. | Proc Natl Acad Sci U S A | 2004 May 18 |
6 |
56 | 15249423 | Inhibitory effects of digoxin and digitoxin on corticosterone production in rat zona fasciculata-reticularis cells. | Br J Pharmacol | 2004 Aug |
1 |
57 | 15554746 | Fab antibody fragments: some applications in clinical toxicology. | Drug Saf | 2004 |
1 |
58 | 15602003 | Digitalis-induced signaling by Na+/K+-ATPase in human breast cancer cells. | Mol Pharmacol | 2005 Mar |
1 |
59 | 15983368 | Cardiac glycosides inhibit TNF-alpha/NF-kappaB signaling by blocking recruitment of TNF receptor-associated death domain to the TNF receptor. | Proc Natl Acad Sci U S A | 2005 Jul 5 |
1 |
60 | 16084692 | Calcium-dependent regulation of NF-(kappa)B activation in cystic fibrosis airway epithelial cells. | Cell Signal | 2006 May |
2 |
61 | 16175571 | Mechanisms of digoxin and digitoxin on the production of corticosterone in zona fasciculata-reticularis cells of ovariectomized rats. | J Cell Biochem | 2006 Feb 1 |
2 |
62 | 16243970 | The highly conserved cardiac glycoside binding site of Na,K-ATPase plays a role in blood pressure regulation. | Proc Natl Acad Sci U S A | 2005 Nov 1 |
1 |
63 | 16668240 | Multiple forms of plant cytochromes p-450. | Plant Physiol | 1991 Jul |
1 |
64 | 16668583 | Lidocaine and ATPase inhibitor interaction with the chloroplast envelope. | Plant Physiol | 1991 Dec |
1 |
65 | 17095614 | Cardiac glycosides as novel inhibitors of human ether-a-go-go-related gene channel trafficking. | J Pharmacol Exp Ther | 2007 Feb |
4 |
66 | 17338573 | De novo approach to 2-deoxy-beta-glycosides: asymmetric syntheses of digoxose and digitoxin. | J Org Chem | 2007 Mar 30 |
1 |
67 | 18080812 | The association of ABCB1 polymorphisms and elevated serum digitoxin concentrations in geriatric patients. | Eur J Clin Pharmacol | 2008 Apr |
5 |
68 | 18289081 | The de novo synthesis of oligosaccharides: application to the medicinal chemistry SAR-study of digitoxin. | Curr Top Med Chem | 2008 |
1 |
69 | 18755149 | Actein inhibits the Na+-K+-ATPase and enhances the growth inhibitory effect of digitoxin on human breast cancer cells. | Biochem Biophys Res Commun | 2008 Oct 31 |
2 |
70 | 19446813 | Digitoxin elicits anti-inflammatory and vasoprotective properties in endothelial cells: Therapeutic implications for the treatment of atherosclerosis? | Atherosclerosis | 2009 Oct |
11 |
71 | 19487957 | Inhibition of the alpha1beta1 isoform of the Na, K-ATPase by 8-methoxycoumestrol without positive inotropic effect in human myocardium--novel aspects of cardiac glycoside pharmacology. | J Cardiovasc Pharmacol | 2009 Jul |
1 |
72 | 20206126 | Cardiac glycosides potently inhibit C-reactive protein synthesis in human hepatocytes. | Biochem Biophys Res Commun | 2010 Mar 26 |
2 |
73 | 20388710 | Selectivity of digitalis glycosides for isoforms of human Na,K-ATPase. | J Biol Chem | 2010 Jun 18 |
1 |
74 | 20850842 | Cardiac glycosides decrease prostate specific antigen expression by down-regulation of prostate derived Ets factor. | J Urol | 2010 Nov |
3 |
75 | 21139994 | Digitoxin activates EGR1 and synergizes with paclitaxel on human breast cancer cells. | J Carcinog | 2010 Nov 18 |
8 |
76 | 21421322 | Synthesis and evaluation of cardiac glycoside mimics as potential anticancer drugs. | Bioorg Med Chem | 2011 Apr 1 |
1 |
77 | 21807619 | Arrhythmogenic adverse effects of cardiac glycosides are mediated by redox modification of ryanodine receptors. | J Physiol | 2011 Oct 1 |
2 |
78 | 22037315 | Digitoxin and a synthetic monosaccharide analog inhibit cell viability in lung cancer cells. | Toxicol Appl Pharmacol | 2012 Jan 1 |
1 |
79 | 22456266 | The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B. | RNA | 2012 May |
8 |
80 | 22484270 | Interaction of tetramethylpyrazine with two serum albumins by a hybrid spectroscopic method. | Spectrochim Acta A Mol Biomol Spectrosc | 2012 Jul |
1 |
81 | 23858296 | Digitoxin induces apoptosis in cancer cells by inhibiting nuclear factor of activated T-cells-driven c-MYC expression. | J Carcinog | 2013 |
9 |
82 | 24045365 | Digitoxin sensitizes glioma cells to TRAIL-mediated apoptosis by upregulation of death receptor 5 and downregulation of survivin. | Anticancer Drugs | 2014 Jan |
11 |
83 | 24065415 | [BNP elevation due to a subdural hematoma - misled by a biomarker]. | Dtsch Med Wochenschr | 2013 Oct |
1 |
84 | 24104877 | Ryanodine receptor phosphorylation by oxidized CaMKII contributes to the cardiotoxic effects of cardiac glycosides. | Cardiovasc Res | 2014 Jan 1 |
1 |
85 | 24124520 | Ouabain, a cardiac glycoside, inhibits the Fanconi anemia/BRCA pathway activated by DNA interstrand cross-linking agents. | PLoS One | 2013 |
4 |
86 | 24231508 | Monosaccharide digitoxin derivative sensitize human non-small cell lung cancer cells to anoikis through Mcl-1 proteasomal degradation. | Biochem Pharmacol | 2014 Mar 1 |
3 |
87 | 24754247 | Interaction of digitalis-like compounds with liver uptake transporters NTCP, OATP1B1, and OATP1B3. | Mol Pharm | 2014 Jun 2 |
1 |
88 | 26119931 | Regulation of CD44E by DARPP-32-dependent activation of SRp20 splicing factor in gastric tumorigenesis. | Oncogene | 2016 Apr 7 |
1 |
89 | 26688208 | Evaluation of the binding interaction between bovine serum albumin and dimethyl fumarate, an anti-inflammatory drug by multispectroscopic methods. | Spectrochim Acta A Mol Biomol Spectrosc | 2016 Mar 5 |
1 |
90 | 26691294 | Digitoxin enhances the growth inhibitory effects of thapsigargin and simvastatin on ER negative human breast cancer cells. | Fitoterapia | 2016 Mar |
5 |
91 | 26708294 | Heterogeneous transport of digitalis-like compounds by P-glycoprotein in vesicular and cellular assays. | Toxicol In Vitro | 2016 Apr |
2 |
92 | 26880969 | Formation of Tumorspheres with Increased Stemness without External Mitogens in a Lung Cancer Model. | Stem Cells Int | 2016 |
1 |
93 | 26999101 | Compound Library Screening Identified Cardiac Glycoside Digitoxin as an Effective Growth Inhibitor of Gefitinib-Resistant Non-Small Cell Lung Cancer via Downregulation of α-Tubulin and Inhibition of Microtubule Formation. | Molecules | 2016 Mar 18 |
2 |
94 | 27431571 | Cardiac glycosides display selective efficacy for STK11 mutant lung cancer. | Sci Rep | 2016 Jul 19 |
2 |
95 | 27504932 | Chemoresistance of Lung and Breast Cancer Cells Growing Under Prolonged Periods of Serum Starvation. | J Cell Physiol | 2017 Aug |
5 |
96 | 28006108 | Digitoxin for Airway Inflammation in Cystic Fibrosis: Preliminary Assessment of Safety, Pharmacokinetics, and Dose Finding. | Ann Am Thorac Soc | 2017 Feb |
2 |
97 | 28035421 | Digitoxin synergizes with sorafenib to inhibit hepatocelluar carcinoma cell growth without inhibiting cell migration. | Mol Med Rep | 2017 Feb |
2 |
98 | 28410215 | Cardiac glycosides suppress the maintenance of stemness and malignancy via inhibiting HIF-1α in human glioma stem cells. | Oncotarget | 2017 Jun 20 |
10 |
99 | 28511914 | Digitoxin increases sensitivity of glioma stem cells to TRAIL-mediated apoptosis. | Neurosci Lett | 2017 Jul 13 |
10 |
100 | 28688145 | Therapeutic concentrations of digitoxin inhibit endothelial focal adhesion kinase and angiogenesis induced by different growth factors. | Br J Pharmacol | 2017 Sep |
4 |