Digitoxin






117 Article(s)
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1 123547 The reactivity of derivatives of digoxin and digitoxin as measured by the Na-K-atpase displacement assay and by radioimmunoassay. J Lab Clin Med 1975 Apr 2
2 144440 Effect of prophylactic digitalization on the development of myocardial hypertrophy. Am J Physiol 1977 Nov 1
3 218119 Dehydro-digitoxosides of digitoxigenin and digoxigenin: binding to beef heart (Na+ + K+)-ATPase in relation to unchanged digitoxosides. Naunyn Schmiedebergs Arch Pharmacol 1979 Jan 1
4 368816 Reversal of digitalis effects by specific antibodies. Pharmacology 1979 1
5 501928 Some observations on serum concentrations of digitoxin and digoxin. Jpn Heart J 1979 Sep 5
6 581954 Quantitative studies on acid hydrolysis of digitoxin. Arzneimittelforschung 1978 5
7 891591 Binding of 16alpha-gitoxin and its 16-acetate to human serum albumin. Eur J Clin Pharmacol 1977 Jul 19 1
8 914928 Quantitation with high-performance thin-layer chromatography and programmed multiple development with high-performance micro-thin-layer material for drug analyses in biological fluids. J Chromatogr 1977 Nov 11 1
9 1207785 Species differences in plasma binding and tissue uptake of 3H-digitoxin. A comparative study in rats and mice in vivo and in vitro. Naunyn Schmiedebergs Arch Pharmacol 1975 1
10 1469187 Treatment of a patient with severe digitoxin intoxication by Fab fragments of anti-digitalis antibodies. Intensive Care Med 1992 10
11 1944247 Species differences in the toxicity and cytochrome P450 IIIA-dependent metabolism of digitoxin. Mol Pharmacol 1991 Nov 1
12 1997019 Recognition and management of digitalis intoxication: implications for emergency medicine. Am J Emerg Med 1991 Mar 1
13 2004463 Preparation of specific antiserum to digitoxin by using digitoxin hemisuccinate-bovine serum albumin conjugate at the digitoxose C-3' position. Clin Chem 1991 Mar 1
14 2325409 Pronounced and differential effects of ionic strength and pH on testosterone oxidation by membrane-bound and purified forms of rat liver microsomal cytochrome P-450. J Steroid Biochem 1990 Mar 2
15 2702965 Digitoxin in patients with hepatorenal insufficiency after repeated oral administration. Eur Heart J 1989 Jan 2
16 2713547 Mass spectrometric analysis of cardiac glycosides by the desorption/ionization technique potassium ion ionization of desorbed species. Biomed Environ Mass Spectrom 1989 Mar 1
17 2799159 [Acute digitoxin poisoning]. Schweiz Rundsch Med Prax 1989 Aug 15 1
18 2894952 UDP-glucuronosyltransferase activity toward digitoxigenin-monodigitoxoside. Differences in activation and induction properties in rat and mouse liver. Drug Metab Dispos 1988 Jan-Feb 2
19 2945566 The rate of uptake of cardiac glycosides into human cultured cells and the effects of chloroquine on it. Biochem Pharmacol 1986 Oct 15 2
20 3029099 Monovalent cation dependence of tissue plasminogen activator synthesis by HeLa cells. J Biol Chem 1987 Mar 5 1
21 3098175 Digitoxin metabolism by liver microsomal cytochrome P-450 and UDP-glucuronosyltransferase and its role in the protection of rats from digitoxin toxicity by pregnenolone-16 alpha-carbonitrile. Arch Biochem Biophys 1986 Nov 15 2
22 3120728 Studies on the pregnenolone-16 alpha-carbonitrile-inducible form of rat liver microsomal cytochrome P-450 and UDP-glucuronosyltransferase. Biochem Pharmacol 1987 Nov 15 1
23 4261840 Ultrastructural changes in hepatocytes induced by pregnenolone-16a-carbonitrile (PCN). Can J Comp Med 1972 Jul 1
24 4851040 Cleavage by beta-glucuronidase of the water-soluble metabolites of digitoxin excreted in the bile of control and spironolactone-pretreated rats. Toxicol Appl Pharmacol 1974 Mar 1
25 5382549 [Serum concentration and excretion of H3Y digitoxin in humans under normal and pathologic conditions]. Klin Wochenschr 1969 Jul 1 1
26 6085642 A simple system for the investigation of protein binding effects on the renal handling of drugs in an isolated perfused rat kidney preparation. J Pharmacol Methods 1984 Sep 1
27 6094699 Photoaffinity labeling of the ouabain binding site in Na, K-ATPase in developing brine shrimp. J Exp Zool 1984 Sep 1
28 6307757 Use of photolabels to probe the Na,K-ATPase and the beta-adrenergic receptor. Fed Proc 1983 Aug 1
29 6333127 Treatment of severe digitoxin intoxication by digoxin-specific Fab antibody fragments. Acta Cardiol 1984 1
30 6651078 [Reversibility of severe digitoxin poisoning with antidigoxin antibodies]. Ann Med Interne (Paris) 1983 1
31 6652360 The effects of chloroquine and other weak bases on the accumulation and efflux of digoxin and ouabain in HeLa cells. Br J Pharmacol 1983 Aug 1
32 6743195 Positive inotropic effects of digitoxin- and digoxin-glucuronide in human isolated ventricular heart muscle preparations. Basic Res Cardiol 1984 2
33 6752715 Treatment of life-threatening digitalis intoxication with digoxin-specific Fab antibody fragments: experience in 26 cases. N Engl J Med 1982 Nov 25 1
34 6779736 [Treatment of massive digitalis poisoning (20 mg of digitoxin) with anti-digoxin antibody fragments (Fab)]. Arch Mal Coeur Vaiss 1980 Dec 1
35 7162976 [Digitoxin poisoning: reversing ventricular fibrillation with Fab fragments of anti-digoxin antibody]. Nouv Presse Med 1982 Dec 25 2
36 7163640 Digitoxin metabolism by rat, mouse, and rabbit: NADPH requirement and spironolactone effect. Res Commun Chem Pathol Pharmacol 1982 Dec 1
37 7461023 Interindividual differences in the pharmacokinetics of digitoxin and digoxin during long-term treatment. Eur J Clin Pharmacol 1981 Jan 2
38 7905397 Formation of a beta-glucuronidase-resistant glucuronide conjugate of digitoxin by dog liver microsomes. Drug Metab Dispos 1993 Nov-Dec 2
39 8069249 Preparation and antigenic properties of digitoxin-bovine serum albumin conjugates linked at the digitoxose C-3' and C-3" positions. Biol Pharm Bull 1994 Apr 3
40 8069874 One-pot-synthesis of alpha-linked deoxy sugar trisaccharides. Carbohydr Res 1994 Jul 16 1
41 8115274 Massive digitoxin intoxication treated with digoxin-specific antibodies in a child. Pediatr Cardiol 1994 Jan-Feb 3
42 8321833 Development of a sensitive radioimmunoassay for Fab fragments: application to Fab pharmacokinetics in humans. Pharm Res 1993 May 1
43 8372053 The affinity of human serum albumin for [3H]-digitoxin is dependent on albumin concentration. Pharmacol Toxicol 1993 Apr-May 9
44 8832430 Fluorescence detection of cardenolides in reversed-phase high-performance liquid chromatography after post-column derivatization. J Chromatogr B Biomed Appl 1996 Jun 28 1
45 9523981 Role of P-glycoprotein as a secretory mechanism in quinidine absorption from rat small intestine. J Pharm Sci 1998 Mar 2
46 9767368 Effects of digoxin and digitoxin on circadian blood pressure profile in healthy volunteers. Eur J Clin Invest 1998 Sep 2
47 10202961 Characterisation of the binding of digitoxin and acetyldigitoxin to human serum albumin by high-performance affinity chromatography. J Chromatogr B Biomed Sci Appl 1999 Mar 5 2
48 10217348 Effect of digoxin fab antibody on the measurement of total and free digitoxin by fluorescence polarization and a new chemiluminescent immunoassay. Ther Drug Monit 1999 Apr 1
49 10381263 Inhibition of testosterone secretion by digitoxin in rat testicular interstitial cells. J Cell Biochem 1999 Jul 1 6
50 10604823 Sensitive methods for determination of free digitoxin concentration using digitoxin immunoassays: demonstration of elevated free digitoxin concentration caused by digitoxin-phenytoin interaction by applying these new techniques. Ther Drug Monit 1999 Dec 1