methoxyamine






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1 60941 Proceedings: Chemical modification of some hairpin loops of the MS2 genome with the methoxyamine reagent. Arch Int Physiol Biochim 1976 Feb 1
2 1719478 Processing in vitro of an abasic site reacted with methoxyamine: a new assay for the detection of abasic sites formed in vivo. Nucleic Acids Res 1991 Oct 25 2
3 1812071 Interactions of methoxyamine with pyridoxal-5'-phosphate-Schiff's base at the active site of sheep liver serine hydroxymethyltransferase. Indian J Biochem Biophys 1991 Oct-Dec 3
4 6349690 Reaction of apurinic/apyrimidinic sites with [14C]methoxyamine. A method for the quantitative assay of AP sites in DNA. Biochim Biophys Acta 1983 Sep 9 1
5 7213342 The covalent nature of the human antithrombin III--thrombin bond. Biochem J 1980 Sep 1 4
6 7380081 Inhibition of human thrombin by methoxylamine hydrochloride. Int J Biochem 1980 1
7 8119903 Characterization of two cold-sensitive mutants of the beta-galactosidase from Lactobacillus delbruckii subsp. bulgaricus. J Biol Chem 1994 Feb 25 1
8 8221673 Poly(ADP-ribose) polymerase can bind melphalan damaged DNA. Cancer Res 1993 Nov 15 1
9 8439960 Mutagenic processing of ethylation damage in mammalian cells: the use of methoxyamine to study apurinic/apyrimidinic site-induced mutagenesis. Cancer Res 1993 Mar 1 1
10 8482980 Repair of N-methylpurines in DNA from lymphocytes of patients with amyotrophic lateral sclerosis. J Neurol Sci 1993 Apr 1
11 8538647 Identification of a 116 kDa protein able to bind 1,3-bis(2-chloroethyl)-1-nitrosourea-damaged DNA as poly(ADP-ribose) polymerase. Mutat Res 1996 Jan 2 1
12 8960131 A common mechanism of action for the N-glycosylase activity of DNA N-glycosylase/AP lyases from E. coli and T4. Mutat Res 1996 Dec 2 1
13 12017477 Modulation of base excision repair alters cellular sensitivity to UVA1 but not to UVB1. Photochem Photobiol 2002 May 1
14 12439775 Psychobiologic responses to 4 days of increased training and recovery in cyclists. Int J Sports Med 2002 Nov 1
15 14500385 Role of MutSalpha in the recognition of iododeoxyuridine in DNA. Cancer Res 2003 Sep 1 1
16 14522034 Measurement of anti-cancer agent methoxyamine in plasma by tandem mass spectrometry with on-line sample extraction. J Chromatogr B Analyt Technol Biomed Life Sci 2003 Oct 5 1
17 15299078 Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells. Mol Cancer Ther 2004 Aug 1
18 15744347 Enhancement of manumycin A-induced apoptosis by methoxyamine in myeloid leukemia cells. Leukemia 2005 Apr 4
19 16648559 Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence. Mol Cancer Ther 2006 Apr 3
20 17065437 DNA polymerase-beta is expressed early in neurons of Alzheimer's disease brain and is loaded into DNA replication forks in neurons challenged with beta-amyloid. J Neurosci 2006 Oct 25 2
21 17126614 Role for DNA polymerase beta in response to ionizing radiation. DNA Repair (Amst) 2007 Feb 4 3
22 17200364 Manipulation of base excision repair to sensitize ovarian cancer cells to alkylating agent temozolomide. Clin Cancer Res 2007 Jan 1 1
23 18710617 [Effects of manumycin combined with methoxyamine on apoptosis in myeloid leukemia U937 cells]. Ai Zheng 2008 Aug 3
24 19601875 Inhibitory properties of trapping agents: glutathione, potassium cyanide, and methoxylamine, against major human cytochrome p450 isoforms. Drug Metab Lett 2009 Apr 6
25 19726241 Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: use of APE1 small molecule inhibitors to delineate APE1 functions. DNA Repair (Amst) 2009 Nov 2 1
26 21325978 Soy isoflavones augment radiation effect by inhibiting APE1/Ref-1 DNA repair activity in non-small cell lung cancer. J Thorac Oncol 2011 Apr 2
27 21377995 N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide. Neuro Oncol 2011 May 3
28 22237209 Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair. Cell Death Dis 2012 Jan 12 1
29 22828727 Methoxyamine sensitizes the resistant glioblastoma T98G cell line to the alkylating agent temozolomide. Clin Exp Med 2013 Nov 3
30 23700323 The cytotoxic effect of β-elemene against malignant glioma is enhanced by base-excision repair inhibitor methoxyamine. J Neurooncol 2013 Jul 1
31 23958474 Differential effects of methoxyamine on doxorubicin cytotoxicity and genotoxicity in MDA-MB-231 human breast cancer cells. Mutat Res Genet Toxicol Environ Mutagen 2013 Oct 9 4
32 26579709 IDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer Cells. PLoS One 2015 2
33 26602448 Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone. Sci Rep 2015 Nov 25 2
34 27612654 In vitro effects of photodynamic therapy induced by chloroaluminum phthalocyanine nanoemulsion. Photodiagnosis Photodyn Ther 2016 Dec 1
35 29983447 Rotational spectrum of methoxyamine up to 480 GHz: a laboratory study and astronomical search. Astron Astrophys 2018 Jan 1
36 30036687 Bromo-dragonfly, a psychoactive benzodifuran, is resistant to hepatic metabolism and potently inhibits monoamine oxidase A. Toxicol Lett 2018 Oct 1 1
37 32370496 EGFR Inhibitor Gefitinib Induces Cardiotoxicity through the Modulation of Cardiac PTEN/Akt/FoxO3a Pathway and Reactive Metabolites Formation: <i>In Vivo</i> and <i>in Vitro</i> Rat Studies. Chem Res Toxicol 2020 Jul 20 1
38 33216844 Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas. Oncotarget 2020 Nov 3 2
39 34616737 Chemical Inhibition of Apurinic-Apyrimidinic Endonuclease 1 Redox and DNA Repair Functions Affects the Inflammatory Response via Different but Overlapping Mechanisms. Front Cell Dev Biol 2021 2
40 35089032 Miscoding and DNA Polymerase Stalling by Methoxyamine-Adducted Abasic Sites. Chem Res Toxicol 2022 Feb 21 1