thioflavin T






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1 1438289 Deposition of beta/A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxyl-terminal fragment of the Alzheimer amyloid precursor in the brain. Proc Natl Acad Sci U S A 1992 Nov 15 1
2 1672808 Glutamate-, glutaminase-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease. Ann Neurol 1991 Feb 1
3 1759562 Senile dementia of the Alzheimer type: is there a correlation between entorhinal cortex and dentate gyrus lesions? Acta Neuropathol 1991 2
4 2413088 Cortical neurons immunoreactive with antisera against neuropeptide Y are altered in Alzheimer's-type dementia. J Comp Neurol 1985 Aug 22 3
5 2456021 Alzheimer's disease. A double-labeling immunohistochemical study of senile plaques. Am J Pathol 1988 Jul 1
6 2513582 Alpha 1-antichymotrypsin in brain aging and disease. Prog Clin Biol Res 1989 1
7 2886516 Somatostatin immunoreactive neurons in the human hippocampus and cortex shown by immunogold/silver intensification on vibratome sections: coexistence with neuropeptide Y neurons, and effects in Alzheimer-type dementia. J Comp Neurol 1987 Jun 8 1
8 3144799 Cortical angiopathy in Alzheimer's disease: the formation of dystrophic perivascular neurites is related to the exudation of amyloid fibrils from the pathological vessels. Virchows Arch A Pathol Anat Histopathol 1988 1
9 3318271 The comparative immunoreactivities of brain amyloids in Alzheimer's disease and scrapie. Acta Neuropathol 1987 1
10 3794758 Senile plaques are located between apical dendritic clusters. J Neuropathol Exp Neurol 1987 Jan 1
11 6505701 Evidence for cholinergic neurites in senile plaques. Science 1984 Dec 21 1
12 6514105 Acetylcholinesterase activity in senile plaques of aged macaques. Neurobiol Aging 1984 Fall 1
13 7639340 Chemical and immunological heterogeneity of fibrillar amyloid in plaques of Alzheimer's disease and Down's syndrome brains revealed by confocal microscopy. Am J Pathol 1995 Aug 4
14 7824054 Apolipoprotein E-immunoreactivity in aged rhesus monkey cortex: colocalization with amyloid plaques. Neurobiol Aging 1994 Sep-Oct 1
15 7852387 The alpha-helical to beta-strand transition in the amino-terminal fragment of the amyloid beta-peptide modulates amyloid formation. J Biol Chem 1995 Feb 17 1
16 7977635 Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro. Am J Pathol 1994 Nov 3
17 8059599 Pathological alterations of the cerebral microvasculature in Alzheimer's disease and related dementing disorders. Acta Neuropathol 1994 2
18 8197133 Advanced glycation end products contribute to amyloidosis in Alzheimer disease. Proc Natl Acad Sci U S A 1994 May 24 1
19 8292358 An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brain. Neuron 1994 Jan 2
20 8313943 Increased immunoreactivity for Jun- and Fos-related proteins in Alzheimer's disease: association with pathology. Exp Neurol 1994 Feb 2
21 8402154 Differing patterns of aberrant neuronal sprouting in Alzheimer's disease with and without Lewy bodies. Brain Res 1993 Jul 23 2
22 8453378 Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution. Protein Sci 1993 Mar 1
23 8525803 Relationship of amyloid beta/A4 protein to the neurofibrillary tangles in Guamanian parkinsonism-dementia. Acta Neuropathol 1995 1
24 8532111 Beta amyloid is neurotoxic in hippocampal slice cultures. Neurobiol Aging 1995 Sep-Oct 1
25 8593893 Localization and cell association of C1q in Alzheimer's disease brain. Exp Neurol 1996 Mar 1
26 8791894 Beta-protein immunoreactivity in the human brain after cardiac arrest. Folia Neuropathol 1996 1
27 8954102 Self-assembly of the brain MAP-2 microtubule-binding region into polymeric structures resembling Alzheimer filaments. Biochem Biophys Res Commun 1996 Dec 4 1
28 8955102 In vitro polymerization of embryonic MAP-2c and fragments of the MAP-2 microtubule binding region into structures resembling paired helical filaments. J Biol Chem 1996 Dec 20 1
29 9186492 Stopped-flow kinetics reveal multiple phases of thioflavin T binding to Alzheimer beta (1-40) amyloid fibrils. Arch Biochem Biophys 1997 Jun 15 1
30 9202333 Aggregation state-dependent activation of the classical complement pathway by the amyloid beta peptide. J Neurochem 1997 Jul 2
31 9232632 Metal cations defibrillize the amyloid beta-protein fibrils. Neurochem Res 1997 Jul 1
32 9245692 B cell granule peptides affect human islet amyloid polypeptide (IAPP) fibril formation in vitro. Biochem Biophys Res Commun 1997 Jul 30 1
33 9325095 Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils. J Mol Biol 1997 Sep 26 1
34 9351682 ATP-promoted amyloidosis of an amyloid beta peptide. Neuroreport 1997 Oct 20 1
35 9403484 Butyrylcholinesterase in the life cycle of amyloid plaques. Ann Neurol 1997 Dec 2
36 9475506 Brain acetylcholinesterase promotes amyloid-beta-peptide aggregation but does not hydrolyze amyloid precursor protein peptides. Neurochem Res 1998 Feb 1
37 9514645 The in vitro effect of lithocholic acid on the polymerization properties of PiZ alpha-1-antitrypsin. Arch Biochem Biophys 1998 Mar 15 1
38 9546999 The neurotoxicity of amyloid beta protein in aged primates. Amyloid 1998 Mar 1
39 9568695 Sulfate content and specific glycosaminoglycan backbone of perlecan are critical for perlecan's enhancement of islet amyloid polypeptide (amylin) fibril formation. Diabetes 1998 Apr 1
40 9675319 Human recombinant NACP/alpha-synuclein is aggregated and fibrillated in vitro: relevance for Lewy body disease. Brain Res 1998 Jul 20 1
41 9690671 Diffuse, lake-like amyloid-beta deposits in the parvopyramidal layer of the presubiculum in Alzheimer disease. J Neuropathol Exp Neurol 1998 Jul 1
42 9714466 The inhibitory effect of laminin 1 and synthetic peptides deduced from the sequence in the laminin alpha1 chain on Abeta40 fibril formation in vitro. Neurosci Lett 1998 Jul 17 1
43 9751195 In vivo aggregation of beta-amyloid peptide variants. J Neurochem 1998 Oct 1
44 10208537 Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro. Neuroreport 1999 Mar 17 2
45 10514414 Mouse senile amyloid deposition is suppressed by adenovirus-mediated overexpression of amyloid-resistant apolipoprotein A-II. Am J Pathol 1999 Oct 1
46 10521263 The most pathogenic transthyretin variant, L55P, forms amyloid fibrils under acidic conditions and protofilaments under physiological conditions. Biochemistry 1999 Oct 12 1
47 10569934 Interaction between A beta(1-42) and A beta(1-40) in Alzheimer's beta-amyloid fibril formation in vitro. Biochemistry 1999 Nov 23 1
48 10611368 Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 1999 Dec 21 1
49 10611946 Modification of beta 2-microglobulin with D-glucose or 3-deoxyglucosone inhibits A beta 2M amyloid fibril extension in vitro. Amyloid 1999 Dec 1
50 10674423 Evidence for glial-mediated inflammation in aged APP(SW) transgenic mice. Neurobiol Aging 1999 Nov-Dec 2