thymidine 5'-triphosphate






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201 23288848 Transgene expression of Drosophila melanogaster nucleoside kinase reverses mitochondrial thymidine kinase 2 deficiency. J Biol Chem 2013 Feb 15 1
202 23394555 Thymidylate kinase: an old topic brings new perspectives. Curr Med Chem 2013 10
203 23701509 Replication past the butadiene diepoxide-derived DNA adduct S-[4-(N(6)-deoxyadenosinyl)-2,3-dihydroxybutyl]glutathione by DNA polymerases. Chem Res Toxicol 2013 Jun 17 1
204 23715154 Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer. Cancer Discov 2013 Aug 4
205 23717197 "Gate-keeper" residues and active-site rearrangements in DNA polymerase μ help discriminate non-cognate nucleotides. PLoS Comput Biol 2013 2
206 23747089 Evaluation of a treatment and teaching refresher programme for the optimization of intensified insulin therapy in type 1 diabetes. Patient Educ Couns 2013 Oct 3
207 24556140 Molecular cloning and characterization of Brugia malayi thymidylate kinase. Acta Trop 2014 May 2
208 24694247 Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase β. J Am Chem Soc 2014 Apr 16 1
209 24828500 Allosteric regulation of the human and mouse deoxyribonucleotide triphosphohydrolase sterile α-motif/histidine-aspartate domain-containing protein 1 (SAMHD1). J Biol Chem 2014 Jun 27 1
210 25148552 Structural and dynamic characterization of polymerase κ's minor groove lesion processing reveals how adduct topology impacts fidelity. Biochemistry 2014 Sep 9 1
211 25152750 FISH comets show that the salvage enzyme TK1 contributes to gene-specific DNA repair. Front Genet 2014 2
212 25200079 The spontaneous replication error and the mismatch discrimination mechanisms of human DNA polymerase β. Nucleic Acids Res 2014 3
213 25215937 Thymidine kinase 2 enzyme kinetics elucidate the mechanism of thymidine-induced mitochondrial DNA depletion. Biochemistry 2014 Oct 7 1
214 25288794 Structural basis of allosteric activation of sterile α motif and histidine-aspartate domain-containing protein 1 (SAMHD1) by nucleoside triphosphates. J Biol Chem 2014 Nov 21 1
215 25474551 Increased and imbalanced dNTP pools symmetrically promote both leading and lagging strand replication infidelity. PLoS Genet 2014 Dec 1
216 25538242 Yeast DNA polymerase ϵ catalytic core and holoenzyme have comparable catalytic rates. J Biol Chem 2015 Feb 6 1
217 25572391 Defective repair of uracil causes telomere defects in mouse hematopoietic cells. J Biol Chem 2015 Feb 27 1
218 26208523 The 1,2-Diaminocyclohexane Carrier Ligand in Oxaliplatin Induces p53-Dependent Transcriptional Repression of Factors Involved in Thymidylate Biosynthesis. Mol Cancer Ther 2015 Oct 3
219 26315341 A novel viral thymidylate kinase with dual kinase activity. J Bioenerg Biomembr 2015 Oct 2
220 26760297 MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria. PLoS Genet 2016 Jan 1
221 26782170 Exome-wide single-base substitutions in tissues and derived cell lines of the constitutive Fhit knockout mouse. Cancer Sci 2016 Apr 2
222 27009306 Identification of a dTDP-rhamnose biosynthetic pathway that oscillates with the molting cycle in Caenorhabditis elegans. Biochem J 2016 Jun 1 1
223 27668724 Sensitive electrochemical assay of alkaline phosphatase activity based on TdT-mediated hemin/G-quadruplex DNAzyme nanowires for signal amplification. Biosens Bioelectron 2017 Jan 15 4
224 27694439 Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase η. J Biol Chem 2016 Nov 11 1
225 28186504 A defective dNTP pool hinders DNA replication in cell cycle-reactivated terminally differentiated muscle cells. Cell Death Differ 2017 May 1
226 28272441 Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι. Sci Rep 2017 Mar 8 1
227 28411822 Label-free and sensitive assay for deoxyribonuclease I activity based on enzymatically-polymerized superlong poly(thymine)-hosted fluorescent copper nanoparticles. Talanta 2017 Jul 1 2
228 28427352 Point of sampling detection of Zika virus within a multiplexed kit capable of detecting dengue and chikungunya. BMC Infect Dis 2017 Apr 20 2
229 28722177 Metformin-induced alterations in nucleotide metabolism cause 5-fluorouracil resistance but gemcitabine susceptibility in oesophageal squamous cell carcinoma. J Cell Biochem 2018 Jan 2
230 28729658 Differential control of dNTP biosynthesis and genome integrity maintenance by the dUTPase superfamily enzymes. Sci Rep 2017 Jul 20 12
231 28963672 Signal-on electrochemical assay for label-free detection of TdT and BamHI activity based on grown DNA nanowire-templated copper nanoclusters. Anal Bioanal Chem 2017 Nov 4
232 29100421 Pyrimidine metabolic rate limiting enzymes in poorly-differentiated hepatocellular carcinoma are signature genes of cancer stemness and associated with poor prognosis. Oncotarget 2017 Sep 29 2
233 29301983 Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase β. Biochem J 2018 Feb 9 2
234 29405473 Inhibition of Dr-dut gene causes DNA damage in planarian. Mol Reprod Dev 2018 Mar 1
235 29903914 Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator. J Biol Chem 2018 Nov 16 2
236 30199284 Thymidylate kinase is critical for DNA repair via ATM-dependent Tip60 complex formation. FASEB J 2019 Feb 5
237 30377280 Combinatorial Loss of the Enzymatic Activities of Viral Uracil-DNA Glycosylase and Viral dUTPase Impairs Murine Gammaherpesvirus Pathogenesis and Leads to Increased Recombination-Based Deletion in the Viral Genome. mBio 2018 Oct 30 1
238 30462295 A genetic screen pinpoints ribonucleotide reductase residues that sustain dNTP homeostasis and specifies a highly mutagenic type of dNTP imbalance. Nucleic Acids Res 2019 Jan 10 1
239 30605521 Uncovering a unique approach for damaged DNA replication: A computational investigation of a mutagenic tobacco-derived thymine lesion. Nucleic Acids Res 2019 Feb 28 2
240 30612642 Monitoring of successive phosphorylations of thymidine using free and immobilized human nucleoside/nucleotide kinases by Flow Injection Analysis with High-Resolution Mass Spectrometry. Anal Chim Acta 2019 Feb 21 4
241 30902068 Enzyme kinetics of dUTPase from the planarian Dugesia ryukyuensis. BMC Res Notes 2019 Mar 22 1
242 31091546 Adequate Structured Inpatient Diabetes Intervention in People With Type 1 Diabetes Improves Metabolic Control and Frequency of Hypoglycaemia. Exp Clin Endocrinol Diabetes 2020 Dec 1
243 31104084 Alkaline phosphatase determination via regulation of enzymatically generated poly(thymine) as a template for fluorescent copper nanoparticle formation. Anal Bioanal Chem 2019 Jul 6
244 31450426 Monitoring of phosphorylation using immobilized kinases by on-line enzyme bioreactors hyphenated with High-Resolution Mass Spectrometry. Talanta 2019 Dec 1 1
245 31796083 Validation of Plasmodium falciparum dUTPase as the target of 5'-tritylated deoxyuridine analogues with anti-malarial activity. Malar J 2019 Dec 3 2
246 31801863 Induction of Kaposi's Sarcoma-Associated Herpesvirus-Encoded Thymidine Kinase (ORF21) by X-Box Binding Protein 1. J Virol 2020 Feb 14 2
247 31910901 Mitochondrial localization of Dictyostelium discoideum dUTPase mediated by its N-terminus. BMC Res Notes 2020 Jan 7 2
248 32345121 Identification of a novel thymidylate kinase activity. Nucleosides Nucleotides Nucleic Acids 2020 2
249 32345222 Basic biochemical characterization of cytosolic enzymes in thymidine nucleotide synthesis in adult rat tissues: implications for tissue specific mitochondrial DNA depletion and deoxynucleoside-based therapy for TK2-deficiency. BMC Mol Cell Biol 2020 Apr 28 2
250 32727257 Resistance to differentiation affects ribo- and deoxyribonucleotide pools and sensitivity to pyrimidine metabolism antagonists in HL60 cells. Nucleosides Nucleotides Nucleic Acids 2020 1