N(6)-carboxymethyllysine






110 Article(s)
Download
PMID
Title
Journal
Pub. Date
#Total Relationship(s)
1 1611683 Identification of the carboxymethyllysine residue in the advanced stage of glycated human serum albumin. Chem Pharm Bull (Tokyo) 1992 Mar 1
2 8887292 Amyloid beta 2-microglobulin is modified with N epsilon-(carboxymethyl)lysine in dialysis-related amyloidosis. Kidney Int 1996 Oct 3
3 9129235 Photo-enhanced modification of human skin elastin in actinic elastosis by N(epsilon)-(carboxymethyl)lysine, one of the glycoxidation products of the Maillard reaction. J Invest Dermatol 1997 May 1
4 9559679 Conversion of Amadori product of Maillard reaction to Nepsilon-(carboxymethyl)lysine in alkaline condition. FEBS Lett 1998 Mar 27 4
5 9650745 Advanced glycation end products co-localized with astrocytes and microglial cells in Alzheimer's disease brain. Acta Neuropathol 1998 Jun 1
6 9767556 N epsilon-(carboxymethyl)lysine in blood from maintenance hemodialysis patients may contribute to dialysis-related amyloidosis. Kidney Int 1998 Oct 1
7 9782569 Genesis of the uraemic syndrome: role of uraemic toxins. Wien Klin Wochenschr 1998 Aug 21 1
8 9846896 Chemical modification of proteins by methylglyoxal. Cell Mol Biol (Noisy-le-grand) 1998 Nov 1
9 10393704 The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation. J Clin Invest 1999 Jul 3
10 10440132 Advanced glycation end products-cytokine-nitric oxide sequence pathway in the development of diabetic nephropathy: aminoguanidine ameliorates the overexpression of tumour necrosis factor-alpha and inducible nitric oxide synthase in diabetic rat glomeruli. Diabetologia 1999 Jul 2
11 10531386 N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression. J Biol Chem 1999 Oct 29 2
12 10969841 Endothelin 1 transcription is controlled by nuclear factor-kappaB in AGE-stimulated cultured endothelial cells. Diabetes 2000 Sep 2
13 11045671 Advanced glycation endproduct-modified superoxide dismutase-1 (SOD1)-positive inclusions are common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutations and transgenic mice expressing human SOD1 with a G85R mutation. Acta Neuropathol 2000 Nov 1
14 11264780 Dialysis-related amyloidosis: pathogenesis focusing on AGE modification. Semin Dial 2001 Mar-Apr 2
15 11287350 Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE. Am J Physiol Endocrinol Metab 2001 May 1
16 11304045 Formation of advanced glycation end-product-modified superoxide dismutase-1 (SOD1) is one of the mechanisms responsible for inclusions common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutation, and transgenic mice expressing human SOD1 gene mutation. Neuropathology 2001 Mar 1
17 11576932 Advanced glycation end products and the progressive course of renal disease. Am J Kidney Dis 2001 Oct 1
18 11700025 RAGE expression and AGE-induced MAP kinase activation in Caco-2 cells. Biochem Biophys Res Commun 2001 Nov 16 2
19 11854121 Advanced glycation end products activate endothelium through signal-transduction receptor RAGE: a mechanism for amplification of inflammatory responses. Circulation 2002 Feb 19 2
20 11978653 Advanced glycation end product precursors impair epidermal growth factor receptor signaling. Diabetes 2002 May 4
21 12239236 Angiotensin II receptor antagonists and angiotensin-converting enzyme inhibitors lower in vitro the formation of advanced glycation end products: biochemical mechanisms. J Am Soc Nephrol 2002 Oct 1
22 12406185 Accumulation of imidazolone, pentosidine and N(epsilon)-(carboxymethyl)lysine in hippocampal CA4 pyramidal neurons of aged human brain. Pathol Int 2002 Sep 1
23 12446618 Renal connective tissue growth factor induction in experimental diabetes is prevented by aminoguanidine. Endocrinology 2002 Dec 1
24 12504085 RAGE-mediated MAPK activation by food-derived AGE and non-AGE products. Biochem Biophys Res Commun 2003 Jan 10 2
25 12663138 Two polyclonal antisera detect different AGE epitopes in human plasma samples. Immunol Lett 2003 Feb 3 1
26 12765963 A role for advanced glycation end products in diminished bone healing in type 1 diabetes. Diabetes 2003 Jun 2
27 12829653 Chronic diabetes increases advanced glycation end products on cardiac ryanodine receptors/calcium-release channels. Diabetes 2003 Jul 1
28 14679299 Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiol Genomics 2003 Dec 16 1
29 15340223 N(epsilon)-(carboxymethyl)lysine proliferated CD34(+) cells from rat choroidal explant in culture. Biol Pharm Bull 2004 Sep 1
30 15663474 Protein glycation, oxidation and nitration adduct residues and free adducts of cerebrospinal fluid in Alzheimer's disease and link to cognitive impairment. J Neurochem 2005 Jan 1
31 15684477 Inhibitory effect of nifedipine on tumor necrosis factor alpha-induced neovascularization in cultured choroidal explants of streptozotocin-diabetic rat. Biol Pharm Bull 2005 Feb 1
32 16263740 Role of receptor for advanced glycation end-products and signalling events in advanced glycation end-product-induced monocyte chemoattractant protein-1 expression in differentiated mouse podocytes. Nephrol Dial Transplant 2006 Feb 1
33 16365515 Transgenic mice over-expressing dicarbonyl/L-xylulose reductase gene crossed with KK-Ay diabetic model mice: an animal model for the metabolism of renal carbonyl compounds. Exp Anim 2005 Oct 1
34 16374460 The receptor for advanced glycation end products is highly expressed in the skin and upregulated by advanced glycation end products and tumor necrosis factor-alpha. J Invest Dermatol 2006 Feb 2
35 17347584 Pravastatin inhibits carboxymethyllysine-induced monocyte chemoattractant protein 1 expression in podocytes via prevention of signalling events. Nephron Exp Nephrol 2007 2
36 17504976 Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis. FASEB J 2007 Oct 1
37 17567584 Vimentin is the specific target in skin glycation. Structural prerequisites, functional consequences, and role in skin aging. J Biol Chem 2007 Aug 10 2
38 18420491 RAGE and modulation of ischemic injury in the diabetic myocardium. Diabetes 2008 Jul 1
39 18434751 Serum levels of the advanced glycation end products Nepsilon-carboxymethyllysine and pentosidine are not influenced by treatment with the angiotensin receptor II type 1 blocker irbesartan in patients with type 2 diabetic nephropathy and hypertension. Nephron Clin Pract 2008 1
40 18473845 Role of advanced glycation end products in diabetic neuropathy. Curr Pharm Des 2008 1
41 19127169 Advanced glycation end products increase transglutaminase activity in primary porcine tenocytes. J Investig Med 2009 Feb 2
42 19288028 Advanced glycation end products regulate extracellular matrix protein and protease expression by human glomerular mesangial cells. Int J Mol Med 2009 Apr 2
43 19334049 Advanced lipoxidation end-products mediate lipid-induced glomerular injury: role of receptor-mediated mechanisms. J Pathol 2009 Jul 1
44 19397970 Beneficial effects of Chinese prescription Kangen-karyu on diabetes associated with hyperlipidemia, advanced glycation endproducts, and oxidative stress in streptozotocin-induced diabetic rats. J Ethnopharmacol 2009 Jul 15 2
45 19739013 Characterization of anti-advanced glycation end product antibodies to nonenzymatically lysine-derived and arginine-derived glycated products. J Immunoassay Immunochem 2009 1
46 19811526 High plasma levels of the soluble receptor for advanced glycation endproducts in patients with symptomatic carotid atherosclerosis. Eur J Clin Invest 2009 Dec 1
47 19962413 Diabetes-associated changes and role of N epsilon-(carboxymethyl)lysine in big ET-1-induced coronary vasoconstriction. Peptides 2010 Feb 1
48 20067962 Increased toll-like receptor (TLR) activation and TLR ligands in recently diagnosed type 2 diabetic subjects. Diabetes Care 2010 Apr 2
49 20157260 Effects of increased iron intake during the neonatal period on the brain of adult AbetaPP/PS1 transgenic mice. J Alzheimers Dis 2010 2
50 20649531 Glycoxidative stress-induced mitophagy modulates mitochondrial fates. Ann N Y Acad Sci 2010 Jul 2