Pyruvaldehyde






895 Article(s)
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101 11988071 Chromatographic assay of glycation adducts in human serum albumin glycated in vitro by derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and intrinsic fluorescence. Biochem J 2002 May 15 4
102 12002523 Effects of thermal denaturation on protein glycation. Life Sci 2002 Mar 1 2
103 12076520 Expression of rat liver glutathione-S-transferase GSTA5 in cell lines provides increased resistance to alkylating agents and toxic aldehydes. Chem Biol Interact 2002 May 20 1
104 12110033 Efficient in vitro lowering of carbonyl stress by the glyoxalase system in conventional glucose peritoneal dialysis fluid. Kidney Int 2002 Aug 9
105 12359232 Semicarbazide-sensitive amine oxidase in aortic smooth muscle cells mediates synthesis of a methylglyoxal-AGE: implications for vascular complications in diabetes. Biochem Biophys Res Commun 2002 Oct 4 4
106 12504894 Methylglyoxal-bovine serum albumin stimulates tumor necrosis factor alpha secretion in RAW 264.7 cells through activation of mitogen-activating protein kinase, nuclear factor kappaB and intracellular reactive oxygen species formation. Arch Biochem Biophys 2003 Jan 15 4
107 12527413 Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes. Biochim Biophys Acta 2003 Jan 20 6
108 12572858 Regulation of the glyoxalase pathway in human brain microvascular endothelium: effects of troglitazone and tertiary butylhydroperoxide. Endothelium 2002 2
109 12601626 Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes. Metabolism 2003 Feb 1
110 12604218 Up-regulation of aldose reductase by the substrate, methylglyoxal. Chem Biol Interact 2003 Feb 1 14
111 12605598 Protective effect of creatine against inhibition by methylglyoxal of mitochondrial respiration of cardiac cells. Biochem J 2003 Jun 1 1
112 12631075 Methylglyoxal induces apoptosis through activation of p38 mitogen-activated protein kinase in rat mesangial cells. Kidney Int 2003 Mar 4
113 12647305 Involvement of MEKK1/ERK/P21Waf1/Cip1 signal transduction pathway in inhibition of IGF-I-mediated cell growth response by methylglyoxal. J Cell Biochem 2003 Apr 15 5
114 12686132 Physiological and pathological implications of semicarbazide-sensitive amine oxidase. Biochim Biophys Acta 2003 Apr 11 1
115 12815061 Rapid suppression of mitochondrial permeability transition by methylglyoxal. Role of reversible arginine modification. J Biol Chem 2003 Sep 12 3
116 12938820 Single exposure of mesothelial cells to glucose degradation products (GDPs) yields early advanced glycation end-products (AGEs) and a proinflammatory response. Perit Dial Int 2003 May-Jun 2
117 12962499 Enhancement of chaperone function of alpha-crystallin by methylglyoxal modification. Biochemistry 2003 Sep 16 1
118 12965214 Methylglyoxal modifies heat shock protein 27 in glomerular mesangial cells. FEBS Lett 2003 Sep 11 4
119 14556652 Investigation of metal binding and activation of Escherichia coli glyoxalase I: kinetic, thermodynamic and mutagenesis studies. Biochem J 2004 Jan 15 1
120 14556850 Scavenging system efficiency is crucial for cell resistance to ROS-mediated methylglyoxal injury. Free Radic Biol Med 2003 Oct 15 2
121 14577607 Metabolism, not autoxidation, plays a role in alpha-oxoaldehyde- and reducing sugar-induced erythrocyte GSH depletion: relevance for diabetes mellitus. Mol Cell Biochem 2003 Oct 1
122 14641060 Glyoxalase I--structure, function and a critical role in the enzymatic defence against glycation. Biochem Soc Trans 2003 Dec 1
123 14641072 Anti-AGEing defences against Alzheimer's disease. Biochem Soc Trans 2003 Dec 1
124 14675555 Prevention of fructose-induced hypertension by dietary vitamins. Clin Biochem 2004 Jan 1
125 14757937 Advanced glycation endproduct precursor alters intracellular amyloid-beta/A beta PP carboxy-terminal fragment aggregation and cytotoxicity. J Alzheimers Dis 2003 Dec 1
126 14978257 Phorbol 12-myristate 13-acetate protects Jurkat cells from methylglyoxal-induced apoptosis by preventing c-Jun N-terminal kinase-mediated leakage of cytochrome c in an extracellular signal-regulated kinase-dependent manner. Mol Pharmacol 2004 Mar 5
127 14991464 Pentoxyphylline and propentophylline are inhibitors of TNF-alpha release in monocytes activated by advanced glycation endproducts. J Neural Transm (Vienna) 2004 Mar 1
128 15040952 Yeast cells display a regulatory mechanism in response to methylglyoxal. FEMS Yeast Res 2004 Mar 9
129 15051519 Methylglyoxal induces oxidative stress-dependent cell injury and up-regulation of interleukin-1beta and nerve growth factor in cultured hippocampal neuronal cells. Brain Res 2004 May 1 1
130 15161867 Effect of dicarbonyl modification of fibronectin on retinal capillary pericytes. Invest Ophthalmol Vis Sci 2004 Jun 3
131 15240103 Methylglyoxal induces apoptosis through activation of p38 MAPK in rat Schwann cells. Biochem Biophys Res Commun 2004 Jul 30 4
132 15281912 Argpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy. Biochem J 2005 Jan 15 1
133 15329410 A trypanothione-dependent glyoxalase I with a prokaryotic ancestry in Leishmania major. Proc Natl Acad Sci U S A 2004 Sep 7 1
134 15367692 Activity of the Yap1 transcription factor in Saccharomyces cerevisiae is modulated by methylglyoxal, a metabolite derived from glycolysis. Mol Cell Biol 2004 Oct 5
135 15454255 Methotrexate inhibits the glyoxalase system in vivo in children with acute lymphoid leukaemia. Eur J Cancer 2004 Oct 1
136 15475166 The characterisation and functional analysis of the human glyoxalase-1 gene using methods of bioinformatics. Gene 2004 Oct 13 1
137 15496428 The gene for paroxysmal non-kinesigenic dyskinesia encodes an enzyme in a stress response pathway. Hum Mol Genet 2004 Dec 15 1
138 15520007 Methylglyoxal, a metabolite derived from glycolysis, functions as a signal initiator of the high osmolarity glycerol-mitogen-activated protein kinase cascade and calcineurin/Crz1-mediated pathway in Saccharomyces cerevisiae. J Biol Chem 2005 Jan 7 6
139 15544624 Differential expression of receptors for advanced glycation end-products in peritoneal mesothelial cells exposed to glucose degradation products. Clin Exp Immunol 2004 Dec 4
140 15759051 The pro-oxidant role of methylglyoxal in mesenteric artery smooth muscle cells. Can J Physiol Pharmacol 2005 Jan 4
141 15773992 The HOG MAP kinase pathway is required for the induction of methylglyoxal-responsive genes and determines methylglyoxal resistance in Saccharomyces cerevisiae. Mol Microbiol 2005 Apr 9
142 15814533 Glucose degradation products downregulate ZO-1 expression in human peritoneal mesothelial cells: the role of VEGF. Nephrol Dial Transplant 2005 Jul 1
143 15887245 Curcumin prevents methylglyoxal-induced oxidative stress and apoptosis in mouse embryonic stem cells and blastocysts. J Cell Physiol 2005 Dec 3
144 15952936 Alphab-crystallin-assisted reactivation of glucose-6-phosphate dehydrogenase upon refolding. Biochem J 2005 Oct 15 1
145 15965083 Curcumin inhibits ROS formation and apoptosis in methylglyoxal-treated human hepatoma G2 cells. Ann N Y Acad Sci 2005 May 4
146 16037232 Methylglyoxal can modify GAPDH activity and structure. Ann N Y Acad Sci 2005 Jun 6
147 16037234 Methylglyoxal induces apoptosis through oxidative stress-mediated activation of p38 mitogen-activated protein kinase in rat Schwann cells. Ann N Y Acad Sci 2005 Jun 6
148 16037235 Dicarbonyl stress and apoptosis of vascular cells: prevention by alphaB-crystallin. Ann N Y Acad Sci 2005 Jun 4
149 16037241 Methylglyoxal, glyoxal, and their detoxification in Alzheimer's disease. Ann N Y Acad Sci 2005 Jun 3
150 16046286 A novel HPLC procedure for detection and quantification of aminoacetone, a precursor of methylglyoxal, in biological samples. J Chromatogr B Analyt Technol Biomed Life Sci 2005 Sep 25 2