| 1 | 1458471 | Effects of ketoconazole on the proliferation and cell cycle of human cancer cell lines. | Cancer Res | 1992 Dec 15 |
1 |
| 2 | 1495014 | Stereoisomers of ketoconazole: preparation and biological activity. | J Med Chem | 1992 Jul 24 |
1 |
| 3 | 2091733 | Biochemical basis for the activity and selectivity of oral antifungal drugs. | Br J Clin Pract Suppl | 1990 Sep |
2 |
| 4 | 2128178 | Effects of novel antifungal azole derivatives on the 5-lipoxygenase and cyclooxygenase pathway. | Arzneimittelforschung | 1990 Nov |
1 |
| 5 | 2260347 | Fluconazole: a new triazole antifungal agent. | DICP | 1990 Sep |
1 |
| 6 | 2560935 | 5-Lipoxygenase inhibition by antifungal azole derivatives: new tools for immunosuppression? | Eicosanoids | 1989 |
2 |
| 7 | 2827686 | Comparison of two azole antifungal drugs, ketoconazole, and fluconazole, as modifiers of rat hepatic monooxygenase activity. | Biochem Pharmacol | 1988 Feb 1 |
2 |
| 8 | 3288361 | Cytochrome P450 of fungi: primary target for azole antifungal agents. | Curr Top Med Mycol | 1988 |
8 |
| 9 | 3624255 | Modulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by azole antimycotics requires lanosterol demethylation, but not 24,25-epoxylanosterol formation. | J Biol Chem | 1987 Sep 5 |
1 |
| 10 | 7589528 | Altered P450 activity associated with direct selection for fungal azole resistance. | FEBS Lett | 1995 Oct 30 |
2 |
| 11 | 7600912 | Differential expression of rat microsomal epoxide hydrolase gene by imidazole and triazole antimycotic agents. | Drug Metab Dispos | 1995 Apr |
1 |
| 12 | 7628631 | Resistant P45051A1 activity in azole antifungal tolerant Cryptococcus neoformans from AIDS patients. | FEBS Lett | 1995 Jul 17 |
1 |
| 13 | 7752204 | Synthesis and serotonergic activity of N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine and analogues: potent agonists for 5-HT1D receptors. | J Med Chem | 1995 May 12 |
2 |
| 14 | 7864896 | Mode of action and resistance to azole antifungals associated with the formation of 14 alpha-methylergosta-8,24(28)-dien-3 beta,6 alpha-diol. | Biochem Biophys Res Commun | 1995 Feb 27 |
1 |
| 15 | 7980623 | Selectivity of isoprenoid-containing imidazole antifungal compounds for sterol 14-demethylase P450 (P450(14)DM) and 7-ethoxycoumarin O-deethylase P450 of rat liver microsomes. | Biochem Pharmacol | 1994 Oct 18 |
2 |
| 16 | 8043012 | Differential expression of microsomal epoxide hydrolase gene by azole heterocycles in rats. | Biochem Pharmacol | 1994 Jul 5 |
4 |
| 17 | 8130773 | Carbonic anhydrase activators. VII. Isozyme II activation by bisazolyl-methanes, -ethanes and related azoles. | Biol Pharm Bull | 1993 Dec |
1 |
| 18 | 8289197 | Adenosine deaminase inhibitors: synthesis and structure-activity relationships of 2-hydroxy-3-nonyl derivatives of azoles. | J Med Chem | 1994 Jan 7 |
1 |
| 19 | 8440921 | Direct interaction of antifungal azole-derivatives with calmodulin: a possible mechanism for their therapeutic activity. | J Invest Dermatol | 1993 Mar |
3 |
| 20 | 8520811 | 150 mg fluconazole does not substantially increase the effects of 10 mg midazolam or the plasma midazolam concentrations in healthy subjects. | Int J Clin Pharmacol Ther | 1995 Sep |
1 |
| 21 | 8632420 | Azole endothelin antagonists. 2. Structure-activity studies. | J Med Chem | 1996 Feb 16 |
2 |
| 22 | 8632421 | Azole endothelin antagonists. 3. Using delta log P as a tool to improve absorption. | J Med Chem | 1996 Feb 16 |
1 |
| 23 | 8641300 | Correlation between in vitro resistance to fluconazole and clinical outcome of oropharyngeal candidiasis in HIV-infected patients. | Eur J Clin Microbiol Infect Dis | 1996 Jan |
1 |
| 24 | 8779634 | Synthesis and evaluation of azole-substituted tetrahydronaphthalenes as inhibitors of P450 arom, P450 17, and P450 TxA2. | Arch Pharm (Weinheim) | 1996 May |
1 |
| 25 | 8846621 | Metabolism of drugs by cytochrome P450 3A isoforms. Implications for drug interactions in psychopharmacology. | Clin Pharmacokinet | 1995 |
1 |
| 26 | 8851866 | Novel azole derivatives are antagonists at the inhibitory GABA receptor on the somatic muscle cells of the parasitic nematode Ascaris suum. | Parasitology | 1996 Feb |
1 |
| 27 | 9084959 | Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations. | Clin Pharmacokinet | 1997 Mar |
1 |
| 28 | 9092539 | Characterization of Saccharomyces cerevisiae CYP61, sterol delta22-desaturase, and inhibition by azole antifungal agents. | J Biol Chem | 1997 Apr 11 |
1 |
| 29 | 9131486 | Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans. | J Pharmacokinet Biopharm | 1996 Oct |
1 |
| 30 | 9246018 | Tacrolimus oral bioavailability doubles with coadministration of ketoconazole. | Clin Pharmacol Ther | 1997 Jul |
3 |
| 31 | 9326581 | A yeast sterol auxotroph (erg25) is rescued by addition of azole antifungals and reduced levels of heme. | Proc Natl Acad Sci U S A | 1997 Oct 14 |
5 |
| 32 | 9333052 | Studies of the mechanism of human salivary histatin-5 candidacidal activity with histatin-5 variants and azole-sensitive and -resistant Candida species. | Antimicrob Agents Chemother | 1997 Oct |
2 |
| 33 | 9375500 | Azole antifungals: weak inhibitors of inducible nitric oxide synthase in mouse and human cells. | Mycoses | 1997 Sep |
2 |
| 34 | 9526564 | Novel 17-azolyl steroids, potent inhibitors of human cytochrome 17 alpha-hydroxylase-C17,20-lyase (P450(17) alpha): potential agents for the treatment of prostate cancer. | J Med Chem | 1998 Mar 12 |
1 |
| 35 | 9636844 | Combination immunotherapy and antifungal chemotherapy. | Clin Infect Dis | 1998 Jun |
1 |
| 36 | 9640482 | Syncopal episodes associated with cisapride and concurrent drugs. | Ann Pharmacother | 1998 Jun |
1 |
| 37 | 9660988 | Inhibition of hyphal growth of azole-resistant strains of Candida albicans by triazole antifungal agents in the presence of lactoferrin-related compounds. | Antimicrob Agents Chemother | 1998 Jul |
1 |
| 38 | 9661006 | Fluconazole resistance associated with drug efflux and increased transcription of a drug transporter gene, PDH1, in Candida glabrata. | Antimicrob Agents Chemother | 1998 Jul |
2 |
| 39 | 9661017 | NADPH cytochrome P-450 oxidoreductase and susceptibility to ketoconazole. | Antimicrob Agents Chemother | 1998 Jul |
4 |
| 40 | 9781363 | Enhanced anti-Candida activity of neutrophils and azole antifungal agents in the presence of lactoferrin-related compounds. | Adv Exp Med Biol | 1998 |
3 |
| 41 | 9855331 | Pharmacokinetic drug interactions of vinca alkaloids: summary of case reports. | Pharmacotherapy | 1998 Nov-Dec |
1 |
| 42 | 9884838 | Azole resistance among oral Candida species isolates from AIDS patients under ketoconazole exposure. | Diagn Microbiol Infect Dis | 1998 Nov |
1 |
| 43 | 9890948 | PDR16 and PDR17, two homologous genes of Saccharomyces cerevisiae, affect lipid biosynthesis and resistance to multiple drugs. | J Biol Chem | 1999 Jan 22 |
2 |
| 44 | 10398344 | Characteristics of the heterologously expressed human lanosterol 14alpha-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human and Candida albicans CYP51 with azole antifungal agents. | Yeast | 1999 Jun 30 |
2 |
| 45 | 10445042 | Molecular modelling of lanosterol 14 alpha-demethylase (CYP51) from Saccharomyces cerevisiae via homology with CYP102, a unique bacterial cytochrome P450 isoform: quantitative structure-activity relationships (QSARs) within two related series of antifungal azole derivatives. | J Enzyme Inhib | 1999 |
4 |
| 46 | 10543755 | Genetic analysis of azole resistance by transposon mutagenesis in Saccharomyces cerevisiae. | Antimicrob Agents Chemother | 1999 Nov |
4 |
| 47 | 10543759 | The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents. | Antimicrob Agents Chemother | 1999 Nov |
1 |
| 48 | 10543768 | Overexpression of Erg11p by the regulatable GAL1 promoter confers fluconazole resistance in Saccharomyces cerevisiae. | Antimicrob Agents Chemother | 1999 Nov |
1 |
| 49 | 10592714 | [Adherence and invasion-two pathogenicity factors in bacterial and fungal pathogens]. | Mycoses | 1999 |
1 |
| 50 | 10709776 | Effects of the antifungal agents on oxidative drug metabolism: clinical relevance. | Clin Pharmacokinet | 2000 Feb |
1 |