Topotecan


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290 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 116
2 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 38
3 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_MOUSE Abcg2 Mus musculus 26357 461 23
4 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 21
5 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 19
6 DNA topoisomerase I TOP1_HUMAN TOP1 Homo sapiens 7150 98 15
7 colony stimulating factor 3 CSF3_HUMAN CSF3 Homo sapiens 1440 955 13
8 tyrosyl-DNA phosphodiesterase 1 TYDP1_HUMAN TDP1 Homo sapiens 55775 208 12
9 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 11
10 SCLC1 - SCLC1 Homo sapiens 7864 68 10
11 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 9
12 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 9
13 H2A.X variant histone H2AX_HUMAN H2AX Homo sapiens 3014 412 8
14 phosphoglycolate phosphatase PGP_MOUSE Pgp Mus musculus 67078 756 8
15 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 7
16 mucin 16, cell surface associated MUC16_HUMAN MUC16 Homo sapiens 94025 408 7
17 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 6
18 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 6
19 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 6
20 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 5
21 phosphoglycolate phosphatase PGP_HUMAN PGP Homo sapiens 283871 1342 5
22 ATP binding cassette subfamily B member 6 (Langereis blood group) ABCB6_HUMAN ABCB6 Homo sapiens 10058 793 5
23 colony stimulating factor 2 CSF2_HUMAN CSF2 Homo sapiens 1437 2088 5
24 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 5
25 ubiquitin protein ligase E3A UBE3A_MOUSE Ube3a Mus musculus 22215 25 5
26 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 5
27 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 5
28 ATP-binding cassette, sub-family B (MDR/TAP), member 1B MDR1B_MOUSE Abcb1b Mus musculus 18669 469 4
29 metallothionein 1E MT1E_HUMAN MT1E Homo sapiens 4493 133 4
30 choline phosphotransferase 1 CHPT1_HUMAN CHPT1 Homo sapiens 56994 212 4
31 MYCN proto-oncogene, bHLH transcription factor MYCN_HUMAN MYCN Homo sapiens 4613 374 4
32 topoisomerase (DNA) I TOP1_MOUSE Top1 Mus musculus 21969 54 4
33 CD34 molecule CD34_HUMAN CD34 Homo sapiens 947 1218 4
34 hypoxia inducible factor 1, alpha subunit HIF1A_MOUSE Hif1a Mus musculus 15251 724 4
35 host cell factor C1 HCFC1_HUMAN HCFC1 Homo sapiens 3054 516 4
36 tyrosyl-DNA phosphodiesterase 1 B8JJC1_MOUSE Tdp1 Mus musculus 104884 22 4
37 ATP binding cassette subfamily G member 2 Q38JL0_CANLF ABCG2 Canis lupus familiaris 478472 141 4
38 poly (ADP-ribose) polymerase family, member 1 Q921K2_MOUSE Parp1 Mus musculus 11545 842 3
39 BH3 interacting domain death agonist BID_HUMAN BID Homo sapiens 637 1130 3
40 proprotein convertase subtilisin/kexin type 5 PCSK5_HUMAN PCSK5 Homo sapiens 5125 122 3
41 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 3
42 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 3
43 transformation related protein 53, pseudogene - Trp53-ps Mus musculus 22060 1552 3
44 Fas cell surface death receptor TNR6_HUMAN FAS Homo sapiens 355 474 3
45 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 3
46 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 3
47 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 3
48 RB transcriptional corepressor 1 RB_HUMAN RB1 Homo sapiens 5925 809 3
49 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 3
50 schlafen family member 11 SLN11_HUMAN SLFN11 Homo sapiens 91607 41 3