pregna-4,17-diene-3,16-dione


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169 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 nuclear receptor subfamily 1 group H member 4 NR1H4_HUMAN NR1H4 Homo sapiens 9971 443 25
2 nuclear receptor subfamily 1, group H, member 4 NR1H4_MOUSE Nr1h4 Mus musculus 20186 350 21
3 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 8
4 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 7
5 xenotropic and polytropic retrovirus receptor 1 XPR1_HUMAN XPR1 Homo sapiens 9213 205 7
6 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 7
7 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 7
8 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 6
9 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 6
10 ATP binding cassette subfamily B member 11 ABCBB_HUMAN ABCB11 Homo sapiens 8647 226 5
11 prostaglandin-endoperoxide synthase 2 PGH2_HUMAN PTGS2 Homo sapiens 5743 2572 5
12 nuclear receptor subfamily 1 group I member 2 NR1I2_HUMAN NR1I2 Homo sapiens 8856 820 4
13 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 3
14 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 3
15 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 3
16 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 3
17 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 3
18 nuclear receptor subfamily 1, group H, member 4 NR1H4_RAT Nr1h4 Rattus norvegicus 60351 132 3
19 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 3
20 mitogen-activated protein kinase 3 MK03_MOUSE Mapk3 Mus musculus 26417 1527 3
21 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 3
22 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 3
23 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 3
24 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 3
25 caudal type homeobox 2 CDX2_HUMAN CDX2 Homo sapiens 1045 166 3
26 NFKB inhibitor alpha IKBA_HUMAN NFKBIA Homo sapiens 4792 1043 3
27 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 2
28 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 2
29 brain derived neurotrophic factor BDNF_MOUSE Bdnf Mus musculus 12064 1186 2
30 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 2
31 peroxisome proliferator-activated receptor gamma PPARG_RAT Pparg Rattus norvegicus 25664 909 2
32 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 2
33 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 2
34 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 2
35 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 2
36 matrix metallopeptidase 2 MMP2_HUMAN MMP2 Homo sapiens 4313 2342 2
37 heme oxygenase 1 HMOX1_HUMAN HMOX1 Homo sapiens 3162 1764 2
38 nuclear receptor subfamily 1 group I member 3 NR1I3_HUMAN NR1I3 Homo sapiens 9970 473 2
39 ATP citrate lyase ACLY_HUMAN ACLY Homo sapiens 47 188 2
40 nuclear receptor subfamily 0 group B member 2 NR0B2_HUMAN NR0B2 Homo sapiens 8431 270 2
41 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 2
42 toll like receptor 4 TLR4_HUMAN TLR4 Homo sapiens 7099 1426 2
43 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 2
44 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Q8R427_RAT Abcb1b Rattus norvegicus 24646 765 2
45 protein tyrosine phosphatase non-receptor type 6 PTN6_HUMAN PTPN6 Homo sapiens 5777 273 2
46 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 2
47 cytochrome P450 family 7 subfamily A member 1 CP7A1_HUMAN CYP7A1 Homo sapiens 1581 195 2
48 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 2
49 DNA damage inducible transcript 3 DDIT3_HUMAN DDIT3 Homo sapiens 1649 1082 2
50 nitric oxide synthase 2 NOS2_RAT Nos2 Rattus norvegicus 24599 1861 2