2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide


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120 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 60
2 mitogen-activated protein kinase kinase 1 MP2K1_HUMAN MAP2K1 Homo sapiens 5604 739 31
3 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 23
4 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 22
5 midkine MK_MOUSE Mdk Mus musculus 17242 501 12
6 mitogen-activated protein kinase kinase 1 MP2K1_MOUSE Map2k1 Mus musculus 26395 224 10
7 mitogen-activated protein kinase 3 MK03_MOUSE Mapk3 Mus musculus 26417 1527 7
8 mitogen-activated protein kinase 1 MK01_MOUSE Mapk1 Mus musculus 26413 1992 7
9 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 6
10 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 5
11 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 4
12 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 4
13 mitogen-activated protein kinase 7 MK07_HUMAN MAPK7 Homo sapiens 5598 179 4
14 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 3
15 BCL2 like 11 B2L11_HUMAN BCL2L11 Homo sapiens 10018 399 3
16 ABL proto-oncogene 1, non-receptor tyrosine kinase ABL1_HUMAN ABL1 Homo sapiens 25 989 3
17 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 3
18 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 3
19 zinc fingers and homeoboxes 2 ZHX2_HUMAN ZHX2 Homo sapiens 22882 627 2
20 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Q3UTR7_MOUSE Agt Mus musculus 11606 860 2
21 Kirsten rat sarcoma viral oncogene homolog RASK_MOUSE Kras Mus musculus 16653 464 2
22 zinc fingers and homeoboxes 2 ZHX2_MOUSE Zhx2 Mus musculus 387609 161 2
23 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 2
24 cyclin dependent kinase 1 CDK1_HUMAN CDK1 Homo sapiens 983 1023 2
25 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 2
26 cyclin dependent kinase inhibitor 1A CDN1A_HUMAN CDKN1A Homo sapiens 1026 1631 2
27 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 2
28 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 2
29 Braf transforming gene BRAF_MOUSE Braf Mus musculus 109880 159 2
30 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 2
31 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 2
32 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 2
33 mitogen activated protein kinase 3 MK03_RAT Mapk3 Rattus norvegicus 50689 1665 2
34 mitogen-activated protein kinase kinase 2 MP2K2_HUMAN MAP2K2 Homo sapiens 5605 75 2
35 EPH receptor B2 EPHB2_HUMAN EPHB2 Homo sapiens 2048 321 2
36 mitogen-activated protein kinase 14 MK14_MOUSE Mapk14 Mus musculus 26416 2012 2
37 chemokine (C-C motif) ligand 2 CCL2_MOUSE Ccl2 Mus musculus 20296 1060 2
38 cytochrome P450 family 1 subfamily A member 1 CP1A1_HUMAN CYP1A1 Homo sapiens 1543 1459 1
39 epidermal growth factor EGF_HUMAN EGF Homo sapiens 1950 1636 1
40 FBJ osteosarcoma oncogene FOS_MOUSE Fos Mus musculus 14281 1086 1
41 Rho/Rac guanine nucleotide exchange factor 2 ARHG2_HUMAN ARHGEF2 Homo sapiens 9181 136 1
42 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 1
43 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 1
44 amyloid beta precursor protein A4_HUMAN APP Homo sapiens 351 3390 1
45 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 1
46 v-raf-leukemia viral oncogene 1 RAF1_MOUSE Raf1 Mus musculus 110157 224 1
47 insulin like growth factor 1 IGF1_HUMAN IGF1 Homo sapiens 3479 1917 1
48 adrenoceptor beta 2 ADRB2_HUMAN ADRB2 Homo sapiens 154 772 1
49 Fos proto-oncogene, AP-1 transcription factor subunit FOS_HUMAN FOS Homo sapiens 2353 1431 1
50 prostaglandin-endoperoxide synthase 2 PGH2_MOUSE Ptgs2 Mus musculus 19225 1538 1