tofacitinib


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320 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 Janus kinase 3 JAK3_HUMAN JAK3 Homo sapiens 3718 218 88
2 Janus kinase 1 JAK1_HUMAN JAK1 Homo sapiens 3716 379 76
3 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 43
4 BH3 interacting domain death agonist BID_HUMAN BID Homo sapiens 637 1130 37
5 interferon gamma IFNG_HUMAN IFNG Homo sapiens 3458 3371 32
6 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 32
7 Janus kinase 2 JAK2_HUMAN JAK2 Homo sapiens 3717 1038 25
8 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 24
9 Janus kinase 3 JAK3_MOUSE Jak3 Mus musculus 16453 98 23
10 signal transducer and activator of transcription 1 STAT1_HUMAN STAT1 Homo sapiens 6772 747 17
11 interleukin 17A IL17_HUMAN IL17A Homo sapiens 3605 977 12
12 interferon induced with helicase C domain 1 IFIH1_HUMAN IFIH1 Homo sapiens 64135 106 11
13 interleukin 15 IL15_HUMAN IL15 Homo sapiens 3600 293 10
14 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 10
15 interferon gamma IFNG_MOUSE Ifng Mus musculus 15978 2936 10
16 signal transducer and activator of transcription 5A STA5A_HUMAN STAT5A Homo sapiens 6776 575 9
17 interferon alpha 1 IFNA1_HUMAN IFNA1 Homo sapiens 3439 1490 9
18 C-reactive protein CRP_HUMAN CRP Homo sapiens 1401 2285 9
19 CD4 molecule CD4_HUMAN CD4 Homo sapiens 920 2744 8
20 Janus kinase 3 JAK3_RAT Jak3 Rattus norvegicus 25326 29 8
21 signal transducer and activator of transcription 1 Q8C3V4_MOUSE Stat1 Mus musculus 20846 383 8
22 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 7
23 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 7
24 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 7
25 Janus kinase 1 G3V9W2_RAT Jak1 Rattus norvegicus 84598 86 6
26 tyrosine kinase 2 TYK2_HUMAN TYK2 Homo sapiens 7297 110 6
27 interleukin 4 IL4_HUMAN IL4 Homo sapiens 3565 1529 5
28 interleukin 2 IL2_HUMAN IL2 Homo sapiens 3558 2456 5
29 signal transducer and activator of transcription 3 STAT3_MOUSE Stat3 Mus musculus 20848 1288 5
30 cytochrome P450 family 2 subfamily C member 19 CP2CJ_HUMAN CYP2C19 Homo sapiens 1557 1098 5
31 C-C motif chemokine ligand 2 CCL2_HUMAN CCL2 Homo sapiens 6347 1858 5
32 interleukin 23 subunit alpha IL23A_HUMAN IL23A Homo sapiens 51561 418 5
33 interleukin 6 IL6_RAT Il6 Rattus norvegicus 24498 2269 5
34 metaxin 1 MTX1_HUMAN MTX1 Homo sapiens 4580 251 5
35 colony stimulating factor 2 CSF2_HUMAN CSF2 Homo sapiens 1437 2088 5
36 interleukin 4 IL4_MOUSE Il4 Mus musculus 16189 1488 5
37 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 5
38 interleukin 7 IL7_HUMAN IL7 Homo sapiens 3574 212 5
39 matrix metallopeptidase 3 MMP3_HUMAN MMP3 Homo sapiens 4314 703 4
40 oncostatin M ONCM_HUMAN OSM Homo sapiens 5008 103 4
41 interleukin 10 IL10_HUMAN IL10 Homo sapiens 3586 2075 4
42 interleukin 22 IL22_HUMAN IL22 Homo sapiens 50616 292 4
43 Janus kinase 2 JAK2_MOUSE Jak2 Mus musculus 16452 466 4
44 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 4
45 CD8a molecule CD8A_HUMAN CD8A Homo sapiens 925 1925 4
46 signal transducer and activator of transcription 3 STAT3_RAT Stat3 Rattus norvegicus 25125 689 4
47 Janus kinase 1 B1ASP2_MOUSE Jak1 Mus musculus 16451 123 4
48 interleukin 15 IL15_MOUSE Il15 Mus musculus 16168 191 3
49 TNF superfamily member 11 TNF11_HUMAN TNFSF11 Homo sapiens 8600 766 3
50 interleukin 2 receptor subunit gamma IL2RG_HUMAN IL2RG Homo sapiens 3561 161 3