vandetanib


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159 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 155
2 ret proto-oncogene RET_HUMAN RET Homo sapiens 5979 674 127
3 kinase insert domain receptor VGFR2_HUMAN KDR Homo sapiens 3791 1635 115
4 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 58
5 kinase insert domain protein receptor VGFR2_MOUSE Kdr Mus musculus 16542 475 20
6 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 20
7 epidermal growth factor receptor EGFR_MOUSE Egfr Mus musculus 13649 981 13
8 ret proto-oncogene RET_MOUSE Ret Mus musculus 19713 167 10
9 vascular endothelial growth factor A VEGFA_MOUSE Vegfa Mus musculus 22339 1647 10
10 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 8
11 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 6
12 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 6
13 kinase insert domain receptor VGFR2_RAT Kdr Rattus norvegicus 25589 312 6
14 vascular endothelial growth factor A VEGFA_RAT Vegfa Rattus norvegicus 83785 1424 6
15 fms related receptor tyrosine kinase 4 VGFR3_HUMAN FLT4 Homo sapiens 2324 142 5
16 EPH receptor B2 EPHB2_HUMAN EPHB2 Homo sapiens 2048 321 5
17 epidermal growth factor EGF_HUMAN EGF Homo sapiens 1950 1636 5
18 kinesin family member 5B KINH_HUMAN KIF5B Homo sapiens 3799 59 4
19 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 4
20 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 4
21 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 4
22 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 4
23 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 4
24 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 4
25 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 3
26 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 3
27 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 3
28 ret proto-oncogene RET_RAT Ret Rattus norvegicus 24716 93 3
29 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 3
30 C-X-C motif chemokine receptor 4 CXCR4_HUMAN CXCR4 Homo sapiens 7852 1170 3
31 caspase 7 CASP7_HUMAN CASP7 Homo sapiens 840 333 2
32 solute carrier family 22 member 2 S22A2_HUMAN SLC22A2 Homo sapiens 6582 255 2
33 kinesin family member 5B KINH_MOUSE Kif5b Mus musculus 16573 13 2
34 fms related receptor tyrosine kinase 1 VGFR1_HUMAN FLT1 Homo sapiens 2321 547 2
35 C-X-C motif chemokine ligand 12 SDF1_HUMAN CXCL12 Homo sapiens 6387 628 2
36 nuclear receptor coactivator 4 NCOA4_HUMAN NCOA4 Homo sapiens 8031 81 2
37 Ret oncogene Q7KT06_DROME Ret Drosophila melanogaster 43875 8 2
38 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 2
39 platelet derived growth factor receptor beta PGFRB_HUMAN PDGFRB Homo sapiens 5159 417 2
40 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 2
41 RELA proto-oncogene, NF-kB subunit TF65_HUMAN RELA Homo sapiens 5970 1514 2
42 cytochrome P450 family 4 subfamily F member 3 CP4F3_HUMAN CYP4F3 Homo sapiens 4051 2473 2
43 ETS transcription factor ERG ERG_HUMAN ERG Homo sapiens 2078 1044 2
44 cadherin 1 CADH1_HUMAN CDH1 Homo sapiens 999 1360 2
45 KIT proto-oncogene, receptor tyrosine kinase KIT_HUMAN KIT Homo sapiens 3815 679 2
46 vimentin VIME_HUMAN VIM Homo sapiens 7431 1102 2
47 calcitonin related polypeptide alpha CALCA_HUMAN CALCA Homo sapiens 796 784 2
48 thymidylate synthetase TYSY_HUMAN TYMS Homo sapiens 7298 800 2
49 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 2
50 SEC23 homolog A, COPII coat complex component SC23A_HUMAN SEC23A Homo sapiens 10484 10 1