regorafenib


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259 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 KIT proto-oncogene, receptor tyrosine kinase KIT_HUMAN KIT Homo sapiens 3815 679 32
2 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 32
3 kinase insert domain receptor VGFR2_HUMAN KDR Homo sapiens 3791 1635 30
4 ret proto-oncogene RET_HUMAN RET Homo sapiens 5979 674 21
5 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 19
6 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 19
7 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 19
8 platelet derived growth factor receptor beta PGFRB_HUMAN PDGFRB Homo sapiens 5159 417 18
9 fms related receptor tyrosine kinase 1 VGFR1_HUMAN FLT1 Homo sapiens 2321 547 15
10 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 14
11 zinc fingers and homeoboxes 2 ZHX2_HUMAN ZHX2 Homo sapiens 22882 627 14
12 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 13
13 TEK receptor tyrosine kinase TIE2_HUMAN TEK Homo sapiens 7010 217 13
14 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 11
15 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 10
16 platelet derived growth factor receptor alpha PGFRA_HUMAN PDGFRA Homo sapiens 5156 229 10
17 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 9
18 fibroblast growth factor receptor 1 FGFR1_HUMAN FGFR1 Homo sapiens 2260 405 8
19 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 8
20 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 7
21 alpha fetoprotein FETA_HUMAN AFP Homo sapiens 174 935 6
22 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 6
23 Raf-1 proto-oncogene, serine/threonine kinase RAF1_HUMAN RAF1 Homo sapiens 5894 636 6
24 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 5
25 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 5
26 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 4
27 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 4
28 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 4
29 insulin like growth factor 1 receptor IGF1R_HUMAN IGF1R Homo sapiens 3480 814 4
30 programmed cell death 1 PDCD1_HUMAN PDCD1 Homo sapiens 5133 637 4
31 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 4
32 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 4
33 solute carrier organic anion transporter family member 1B1 SO1B1_HUMAN SLCO1B1 Homo sapiens 10599 575 4
34 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 4
35 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 3
36 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 3
37 nuclear receptor subfamily 0 group B member 2 NR0B2_HUMAN NR0B2 Homo sapiens 8431 270 3
38 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 3
39 C-C motif chemokine ligand 5 CCL5_HUMAN CCL5 Homo sapiens 6352 751 3
40 UDP glucuronosyltransferase family 1 member A1 UD11_HUMAN UGT1A1 Homo sapiens 54658 747 3
41 snail family transcriptional repressor 1 SNAI1_HUMAN SNAI1 Homo sapiens 6615 718 3
42 fms related receptor tyrosine kinase 4 VGFR3_HUMAN FLT4 Homo sapiens 2324 142 3
43 MHC class I polypeptide-related sequence A MICA_HUMAN MICA Homo sapiens 100507436 581 3
44 transforming growth factor alpha TGFA_HUMAN TGFA Homo sapiens 7039 974 3
45 protein tyrosine phosphatase non-receptor type 6 PTN6_HUMAN PTPN6 Homo sapiens 5777 273 3
46 triosephosphate isomerase 1 TPIS_HUMAN TPI1 Homo sapiens 7167 355 3
47 galectin 1 LEG1_HUMAN LGALS1 Homo sapiens 3956 692 3
48 albumin ALBU_HUMAN ALB Homo sapiens 213 5631 3
49 MIR7-3 host gene - MIR7-3HG Homo sapiens 284424 679 3
50 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 2