carfilzomib


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211 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 12
2 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 9
3 DNA damage inducible transcript 3 DDIT3_HUMAN DDIT3 Homo sapiens 1649 1082 7
4 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 6
5 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 6
6 activating transcription factor 4 ATF4_HUMAN ATF4 Homo sapiens 468 451 5
7 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 4
8 NFKB inhibitor alpha IKBA_HUMAN NFKBIA Homo sapiens 4792 1043 4
9 phorbol-12-myristate-13-acetate-induced protein 1 APR_HUMAN PMAIP1 Homo sapiens 5366 357 4
10 proteasome 20S subunit beta 8 PSB8_HUMAN PSMB8 Homo sapiens 5696 43 4
11 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 4
12 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 3
13 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 3
14 exportin 1 XPO1_HUMAN XPO1 Homo sapiens 7514 208 3
15 CD34 molecule CD34_HUMAN CD34 Homo sapiens 947 1218 3
16 proteasome 20S subunit beta 5 PSB5_HUMAN PSMB5 Homo sapiens 5693 34 3
17 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 3
18 potassium calcium-activated channel subfamily M regulatory beta subunit 2 KCMB2_HUMAN KCNMB2 Homo sapiens 10242 1498 3
19 cyclin dependent kinase inhibitor 1B CDN1B_HUMAN CDKN1B Homo sapiens 1027 588 3
20 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 3
21 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 2
22 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 2
23 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 2
24 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 2
25 interferon alpha inducible protein 27 IFI27_HUMAN IFI27 Homo sapiens 3429 662 2
26 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 2
27 heat shock protein 5 BIP_MOUSE Hspa5 Mus musculus 14828 360 2
28 histone deacetylase 9 HDAC9_HUMAN HDAC9 Homo sapiens 9734 707 2
29 parathyroid hormone PTHY_HUMAN PTH Homo sapiens 5741 1284 2
30 adaptor related protein complex 5 subunit beta 1 AP5B1_HUMAN AP5B1 Homo sapiens 91056 202 2
31 microtubule-associated protein 1 light chain 3 beta MLP3B_MOUSE Map1lc3b Mus musculus 67443 134 2
32 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 2
33 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 2
34 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 2
35 chymotrypsin like CTRL_HUMAN CTRL Homo sapiens 1506 36 2
36 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 2
37 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 2
38 lysine methyltransferase 2A KMT2A_HUMAN KMT2A Homo sapiens 4297 332 2
39 endoplasmic reticulum to nucleus signaling 1 ERN1_HUMAN ERN1 Homo sapiens 2081 451 2
40 BCL2 interacting killer BIK_HUMAN BIK Homo sapiens 638 101 2
41 BCL2 antagonist/killer 1 BAK_HUMAN BAK1 Homo sapiens 578 490 2
42 forkhead box O3 FOXO3_HUMAN FOXO3 Homo sapiens 2309 544 2
43 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 2
44 phosphoglycolate phosphatase PGP_HUMAN PGP Homo sapiens 283871 1342 2
45 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 2
46 nuclear paraspeckle assembly transcript 1 (non-protein coding) - Neat1 Mus musculus 66961 63 1
47 ATP binding cassette subfamily A member 4 ABCA4_HUMAN ABCA4 Homo sapiens 24 110 1
48 abl interactor 1 ABI1_HUMAN ABI1 Homo sapiens 10006 42 1
49 X-box binding protein 1 XBP1_MOUSE Xbp1 Mus musculus 22433 192 1
50 proteasome 20S subunit beta 9 PSB9_HUMAN PSMB9 Homo sapiens 5698 70 1