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1341 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 267
2 kallikrein related peptidase 3 KLK3_HUMAN KLK3 Homo sapiens 354 1236 143
3 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 123
4 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 101
5 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 92
6 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 82
7 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 66
8 colony stimulating factor 3 CSF3_HUMAN CSF3 Homo sapiens 1440 955 59
9 androgen receptor ANDR_HUMAN AR Homo sapiens 367 1832 56
10 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 53
11 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 50
12 chromobox 8 CBX8_HUMAN CBX8 Homo sapiens 57332 830 42
13 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 36
14 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 31
15 CD44 molecule (Indian blood group) CD44_HUMAN CD44 Homo sapiens 960 1234 30
16 folate hydrolase 1 FOLH1_HUMAN FOLH1 Homo sapiens 2346 907 25
17 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 25
18 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 25
19 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 20
20 phosphoglycolate phosphatase PGP_HUMAN PGP Homo sapiens 283871 1342 19
21 proprotein convertase subtilisin/kexin type 1 NEC1_HUMAN PCSK1 Homo sapiens 5122 516 19
22 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 19
23 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 19
24 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 19
25 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 18
26 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 18
27 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 18
28 solute carrier organic anion transporter family member 1B3 SO1B3_HUMAN SLCO1B3 Homo sapiens 28234 344 17
29 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 15
30 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 15
31 ATPase secretory pathway Ca2+ transporting 1 AT2C1_HUMAN ATP2C1 Homo sapiens 27032 102 15
32 cytochrome P450 family 1 subfamily B member 1 CP1B1_HUMAN CYP1B1 Homo sapiens 1545 769 14
33 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 14
34 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 14
35 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 14
36 PDZ domain containing 2 PDZD2_HUMAN PDZD2 Homo sapiens 23037 21 14
37 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 14
38 cytochrome P450 family 17 subfamily A member 1 CP17A_HUMAN CYP17A1 Homo sapiens 1586 448 14
39 transferrin TRFE_HUMAN TF Homo sapiens 7018 1795 13
40 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 13
41 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 12
42 prostaglandin-endoperoxide synthase 2 PGH2_HUMAN PTGS2 Homo sapiens 5743 2572 12
43 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 12
44 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 12
45 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 12
46 proteasome 26S subunit, non-ATPase 1 PSMD1_HUMAN PSMD1 Homo sapiens 5707 302 12
47 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 12
48 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 11
49 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 11
50 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 11