ruxolitinib


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364 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 Janus kinase 1 JAK1_HUMAN JAK1 Homo sapiens 3716 379 381
2 Janus kinase 2 JAK2_HUMAN JAK2 Homo sapiens 3717 1038 319
3 Janus kinase 1 B1ASP2_MOUSE Jak1 Mus musculus 16451 123 45
4 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 43
5 Janus kinase 2 JAK2_MOUSE Jak2 Mus musculus 16452 466 39
6 signal transducer and activator of transcription 1 STAT1_HUMAN STAT1 Homo sapiens 6772 747 29
7 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 21
8 interferon gamma IFNG_HUMAN IFNG Homo sapiens 3458 3371 20
9 signal transducer and activator of transcription 5A STA5A_HUMAN STAT5A Homo sapiens 6776 575 17
10 signal transducer and activator of transcription 3 STAT3_MOUSE Stat3 Mus musculus 20848 1288 15
11 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 11
12 ABL proto-oncogene 1, non-receptor tyrosine kinase ABL1_HUMAN ABL1 Homo sapiens 25 989 10
13 interferon alpha 1 IFNA1_HUMAN IFNA1 Homo sapiens 3439 1490 10
14 colony stimulating factor 3 receptor CSF3R_HUMAN CSF3R Homo sapiens 1441 76 10
15 CD4 molecule CD4_HUMAN CD4 Homo sapiens 920 2744 9
16 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 8
17 pericentriolar material 1 PCM1_HUMAN PCM1 Homo sapiens 5108 21 8
18 signal transducer and activator of transcription 1 Q8C3V4_MOUSE Stat1 Mus musculus 20846 383 8
19 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 8
20 signal transducer and activator of transcription 5A STA5A_MOUSE Stat5a Mus musculus 20850 224 7
21 C-reactive protein CRP_HUMAN CRP Homo sapiens 1401 2285 7
22 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 7
23 interferon gamma IFNG_MOUSE Ifng Mus musculus 15978 2936 6
24 CD34 molecule CD34_HUMAN CD34 Homo sapiens 947 1218 6
25 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 6
26 cytokine receptor like factor 2 CRLF2_HUMAN CRLF2 Homo sapiens 64109 49 6
27 BH3 interacting domain death agonist BID_HUMAN BID Homo sapiens 637 1130 6
28 calreticulin CALR_HUMAN CALR Homo sapiens 811 393 6
29 interleukin 15 IL15_HUMAN IL15 Homo sapiens 3600 293 5
30 interleukin 10 IL10_HUMAN IL10 Homo sapiens 3586 2075 5
31 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 5
32 Janus kinase 3 JAK3_HUMAN JAK3 Homo sapiens 3718 218 5
33 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 5
34 interleukin 2 IL2_HUMAN IL2 Homo sapiens 3558 2456 5
35 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 5
36 C-C motif chemokine ligand 2 CCL2_HUMAN CCL2 Homo sapiens 6347 1858 4
37 Janus kinase 1 G3V9W2_RAT Jak1 Rattus norvegicus 84598 86 4
38 C-X-C motif chemokine ligand 10 CXL10_HUMAN CXCL10 Homo sapiens 3627 673 4
39 Janus kinase 2 JAK2_RAT Jak2 Rattus norvegicus 24514 336 4
40 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 4
41 MX dynamin like GTPase 1 MX1_HUMAN MX1 Homo sapiens 4599 158 4
42 cytochrome P450 family 2 subfamily C member 9 CP2C9_HUMAN CYP2C9 Homo sapiens 1559 1244 4
43 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 4
44 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 4
45 interferon beta 1 IFNB_HUMAN IFNB1 Homo sapiens 3456 620 4
46 SET domain containing 2, histone lysine methyltransferase SETD2_HUMAN SETD2 Homo sapiens 29072 121 4
47 interferon alpha 2 IFNA2_HUMAN IFNA2 Homo sapiens 3440 357 3
48 tyrosine kinase 2 TYK2_HUMAN TYK2 Homo sapiens 7297 110 3
49 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 3
50 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 3