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78 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 13
2 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 10
3 insulin INS_HUMAN INS Homo sapiens 3630 7950 7
4 phosphatase and tensin homolog PTEN_MOUSE Pten Mus musculus 19211 532 4
5 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 PREX1_HUMAN PREX1 Homo sapiens 57580 52 3
6 protein kinase C zeta KPCZ_HUMAN PRKCZ Homo sapiens 5590 273 3
7 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 2
8 insulin like growth factor 1 IGF1_HUMAN IGF1 Homo sapiens 3479 1917 2
9 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PK3CA_MOUSE Pik3ca Mus musculus 18706 131 2
10 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma PK3CG_HUMAN PIK3CG Homo sapiens 5294 232 2
11 pyruvate dehydrogenase kinase 1 PDK1_HUMAN PDK1 Homo sapiens 5163 414 2
12 inositol polyphosphate-5-phosphatase D SHIP1_MOUSE Inpp5d Mus musculus 16331 100 2
13 GRB2 associated binding protein 1 GAB1_HUMAN GAB1 Homo sapiens 2549 70 2
14 epidermal growth factor EGF_HUMAN EGF Homo sapiens 1950 1636 2
15 IL2 inducible T cell kinase ITK_HUMAN ITK Homo sapiens 3702 387 1
16 insulin like growth factor 2 mRNA binding protein 1 IF2B1_HUMAN IGF2BP1 Homo sapiens 10642 127 1
17 cytohesin 3 CYH3_HUMAN CYTH3 Homo sapiens 9265 73 1
18 chemokine (C-X-C motif) ligand 12 SDF1_MOUSE Cxcl12 Mus musculus 20315 300 1
19 mal, T cell differentiation protein MAL_HUMAN MAL Homo sapiens 4118 98 1
20 myosin heavy chain 9 MYH9_HUMAN MYH9 Homo sapiens 4627 101 1
21 suppressor of cytokine signaling 3 SOCS3_MOUSE Socs3 Mus musculus 12702 190 1
22 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 1
23 CREB regulated transcription coactivator 2 CRTC2_MOUSE Crtc2 Mus musculus 74343 347 1
24 CREB regulated transcription coactivator 1 CRTC1_MOUSE Crtc1 Mus musculus 382056 993 1
25 sirtuin 1 SIR1_MOUSE Sirt1 Mus musculus 93759 838 1
26 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 1
27 toll like receptor 2 TLR2_HUMAN TLR2 Homo sapiens 7097 778 1
28 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;Receptor protein-tyrosine kinase INSR_CAEEL daf-2 Caenorhabditis elegans 175410 93 1
29 discs large MAGUK scaffold protein 4 DLG4_RAT Dlg4 Rattus norvegicus 29495 230 1
30 signal transducer and activator of transcription 3 STAT3_MOUSE Stat3 Mus musculus 20848 1288 1
31 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PK3CA_HUMAN PIK3CA Homo sapiens 5290 683 1
32 MYD88 innate immune signal transduction adaptor MYD88_HUMAN MYD88 Homo sapiens 4615 440 1
33 pyruvate dehydrogenase kinase 1 Q5FVT5_RAT Pdk1 Rattus norvegicus 116551 51 1
34 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta PK3CD_HUMAN PIK3CD Homo sapiens 5293 775 1
35 sodium channel epithelial 1 subunit gamma SCNNG_HUMAN SCNN1G Homo sapiens 6340 76 1
36 solute carrier family 2 member 4 GLUT4_HUMAN SLC2A4 Homo sapiens 6517 552 1
37 Bruton tyrosine kinase BTK_HUMAN BTK Homo sapiens 695 383 1
38 protein tyrosine phosphatase non-receptor type 11 PTN11_HUMAN PTPN11 Homo sapiens 5781 376 1
39 insulin receptor substrate 1 IRS1_HUMAN IRS1 Homo sapiens 3667 493 1
40 spleen associated tyrosine kinase KSYK_HUMAN SYK Homo sapiens 6850 486 1
41 cell division cycle 42 CDC42_HUMAN CDC42 Homo sapiens 998 455 1
42 Rap guanine nucleotide exchange factor (GEF) 3 RPGF3_MOUSE Rapgef3 Mus musculus 223864 135 1
43 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma PK3CG_MOUSE Pik3cg Mus musculus 30955 126 1
44 paired like homeodomain 2 PITX2_HUMAN PITX2 Homo sapiens 5308 230 1
45 protein kinase C, zeta KPCZ_RAT Prkcz Rattus norvegicus 25522 43 1
46 regulator of G protein signaling 4 RGS4_HUMAN RGS4 Homo sapiens 5999 109 1
47 inositol polyphosphate multikinase IPMK_HUMAN IPMK Homo sapiens 253430 50 1
48 3-phosphoinositide dependent protein kinase 1 PDPK1_HUMAN PDPK1 Homo sapiens 5170 104 1
49 von Willebrand factor VWF_HUMAN VWF Homo sapiens 7450 850 1
50 Phosphatidylinositol 3-kinase age-1 AGE1_CAEEL age-1 Caenorhabditis elegans 174762 39 1