Pub. Date : 1999 Feb 1
PMID : 9917326
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The 6betaB-A site shows a high degree of similarity to a consensus sequence of the binding site of hepatocyte nuclear factor 4 (HNF-4) and also to the 6betaA-A site on the rat CYP3A2 gene promoter region. | 6betab-a | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |
2 | The 6betaB-A site shows a high degree of similarity to a consensus sequence of the binding site of hepatocyte nuclear factor 4 (HNF-4) and also to the 6betaA-A site on the rat CYP3A2 gene promoter region. | 6betaa-a | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |
3 | Our previous study suggested an involvement of the 6betaA-A site in the basal transactivation of CYP3A2 gene using HepG2 cells. | 6betaa-a | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |
4 | In the present study, transactivation through the 6betaB-A and 6betaA-A sites of CYP3A1 and CYP3A2 genes has directly been shown by coexpression of HNF-4 and CYP3A1 or CYP3A2 promoter-reporter fused genes. | 6betab-a | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |
5 | In the present study, transactivation through the 6betaB-A and 6betaA-A sites of CYP3A1 and CYP3A2 genes has directly been shown by coexpression of HNF-4 and CYP3A1 or CYP3A2 promoter-reporter fused genes. | 6betab-a | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |
6 | In the present study, transactivation through the 6betaB-A and 6betaA-A sites of CYP3A1 and CYP3A2 genes has directly been shown by coexpression of HNF-4 and CYP3A1 or CYP3A2 promoter-reporter fused genes. | 6betaa-a | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |
7 | In the present study, transactivation through the 6betaB-A and 6betaA-A sites of CYP3A1 and CYP3A2 genes has directly been shown by coexpression of HNF-4 and CYP3A1 or CYP3A2 promoter-reporter fused genes. | 6betaa-a | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |