Pub. Date : 1996 Feb
PMID : 9816169
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Suramin increases p53 protein levels but does not activate the p53-dependent G1 checkpoint. | Suramin | transformation related protein 53, pseudogene | Mus musculus |
| 2 | We have investigated whether the induction of growth arrest by suramin requires the p53 protein, a tumor suppressor gene product involved in the initiation of growth arrest following DNA damage. | Suramin | transformation related protein 53, pseudogene | Mus musculus |
| 3 | Exposure of NIH-3T3 cells to suramin caused a rapid (1-2 h) increase in the level of p53-DNA-binding activity. | Suramin | transformation related protein 53, pseudogene | Mus musculus |
| 4 | Suramin increases p53 protein levels, but fails to increase p21 mRNA levels or to activate the G1 checkpoint. | Suramin | transformation related protein 53, pseudogene | Mus musculus |