Title : Regulation of apoptosis in mouse hepatocytes and alteration of apoptosis by nongenotoxic carcinogens.

Pub. Date : 1998 Sep

PMID : 9751125






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Bleomycin-induced apoptosis was accompanied by decreases in bcl-2 and bcl-xl and increases in p53, bak, and bax protein levels. Bleomycin transformation related protein 53, pseudogene Mus musculus
2 Bleomycin-induced apoptosis was partially dependent on p53, whereas TGF-beta-induced apoptosis was independent of p53. Bleomycin transformation related protein 53, pseudogene Mus musculus
3 Phenobarbital inhibited both TGF-beta and bleomycin-induced apoptosis and the normal regulation of p53, bcl-2, and bax. Phenobarbital transformation related protein 53, pseudogene Mus musculus