Title : Role of NF-kappaB in the antiproliferative effect of endothelin-1 and tumor necrosis factor-alpha in human hepatic stellate cells. Involvement of cyclooxygenase-2.

Pub. Date : 1998 Sep 4

PMID : 9722548






8 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Activation of NF-kappaB and degradation of IkappaB-alpha were prevented by the NF-kappaB inhibitors sodium salicylate and MG-132. benzyloxycarbonylleucyl-leucyl-leucine aldehyde nuclear factor kappa B subunit 1 Homo sapiens
2 Activation of NF-kappaB and degradation of IkappaB-alpha were prevented by the NF-kappaB inhibitors sodium salicylate and MG-132. benzyloxycarbonylleucyl-leucyl-leucine aldehyde NFKB inhibitor alpha Homo sapiens
3 Activation of NF-kappaB and degradation of IkappaB-alpha were prevented by the NF-kappaB inhibitors sodium salicylate and MG-132. benzyloxycarbonylleucyl-leucyl-leucine aldehyde nuclear factor kappa B subunit 1 Homo sapiens
4 Induction of COX-2 and stimulation of COX activity by ET-1 and TNF-alpha were prevented by sodium salicylate and MG-132, suggesting that activation of NF-kappaB by either factor is needed for stimulation of COX-2. benzyloxycarbonylleucyl-leucyl-leucine aldehyde mitochondrially encoded cytochrome c oxidase II Homo sapiens
5 Induction of COX-2 and stimulation of COX activity by ET-1 and TNF-alpha were prevented by sodium salicylate and MG-132, suggesting that activation of NF-kappaB by either factor is needed for stimulation of COX-2. benzyloxycarbonylleucyl-leucyl-leucine aldehyde endothelin 1 Homo sapiens
6 Induction of COX-2 and stimulation of COX activity by ET-1 and TNF-alpha were prevented by sodium salicylate and MG-132, suggesting that activation of NF-kappaB by either factor is needed for stimulation of COX-2. benzyloxycarbonylleucyl-leucyl-leucine aldehyde tumor necrosis factor Homo sapiens
7 Induction of COX-2 and stimulation of COX activity by ET-1 and TNF-alpha were prevented by sodium salicylate and MG-132, suggesting that activation of NF-kappaB by either factor is needed for stimulation of COX-2. benzyloxycarbonylleucyl-leucyl-leucine aldehyde nuclear factor kappa B subunit 1 Homo sapiens
8 Induction of COX-2 and stimulation of COX activity by ET-1 and TNF-alpha were prevented by sodium salicylate and MG-132, suggesting that activation of NF-kappaB by either factor is needed for stimulation of COX-2. benzyloxycarbonylleucyl-leucyl-leucine aldehyde mitochondrially encoded cytochrome c oxidase II Homo sapiens