Title : Paclitaxel-induced apoptosis is associated with expression and activation of c-Mos gene product in human ovarian carcinoma SKOV3 cells.

Pub. Date : 1998 Aug 15

PMID : 9721872






7 Functional Relationships(s)
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1 Paclitaxel-induced apoptosis is associated with expression and activation of c-Mos gene product in human ovarian carcinoma SKOV3 cells. Paclitaxel MOS proto-oncogene, serine/threonine kinase Homo sapiens
2 We studied whether paclitaxel-induced M-phase arrest and apoptosis are associated with c-Mos gene expression and activation in SKOV3 ovarian carcinoma cells. Paclitaxel MOS proto-oncogene, serine/threonine kinase Homo sapiens
3 Induction of the c-Mos gene expression and activation were determined by Western blot analysis, immunoprecipitation using a polyclonal anti-mos antibody, reverse transcription-PCR assay, and 32P-ATP incorporation into c-Mos protein or the substrate of glutathione S-transferase mitogen-activated protein kinase kinase, respectively. 32p-atp MOS proto-oncogene, serine/threonine kinase Homo sapiens
4 Induction of the c-Mos gene expression and activation were determined by Western blot analysis, immunoprecipitation using a polyclonal anti-mos antibody, reverse transcription-PCR assay, and 32P-ATP incorporation into c-Mos protein or the substrate of glutathione S-transferase mitogen-activated protein kinase kinase, respectively. Glutathione MOS proto-oncogene, serine/threonine kinase Homo sapiens
5 Paclitaxel-induced c-Mos gene expression was completely abrogated by cycloheximide and actinomycin D. Paclitaxel MOS proto-oncogene, serine/threonine kinase Homo sapiens
6 Paclitaxel-induced c-Mos gene expression was completely abrogated by cycloheximide and actinomycin D. Cycloheximide MOS proto-oncogene, serine/threonine kinase Homo sapiens
7 Paclitaxel-induced c-Mos gene expression was completely abrogated by cycloheximide and actinomycin D. Dactinomycin MOS proto-oncogene, serine/threonine kinase Homo sapiens