Title : Formation of DNA etheno adducts in rodents and humans and their role in carcinogenesis.

Pub. Date : 1998

PMID : 9701507






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Hepatic tumours caused by exposure to vinyl chloride in humans and in rats and lung tumours induced by urethane in mice exhibit base pair substitution mutations in the ras and p53 genes which seem to be exposure-specific and consistent with the promutagenic properties of ethenobases. Vinyl Chloride transformation related protein 53, pseudogene Mus musculus
2 Hepatic tumours caused by exposure to vinyl chloride in humans and in rats and lung tumours induced by urethane in mice exhibit base pair substitution mutations in the ras and p53 genes which seem to be exposure-specific and consistent with the promutagenic properties of ethenobases. Urethane transformation related protein 53, pseudogene Mus musculus