Title : Differential CD4-dependent inhibition of JNK but not Erk-2 activities in human naive and memory CD4+ T cell populations.

Pub. Date : 1998 Jul

PMID : 9701025






2 Functional Relationships(s)
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1 In contrast, CD3 mediated JNK activation was inhibited in the memory but not in the naive CD4+ T cell population, whereas JNK activation by phorbol ester or phorbol esters plus Ca2+ ionophore was inhibited by anti-CD4 mAb in both T cell populations. Phorbol Esters mitogen-activated protein kinase 8 Homo sapiens
2 In contrast, CD3 mediated JNK activation was inhibited in the memory but not in the naive CD4+ T cell population, whereas JNK activation by phorbol ester or phorbol esters plus Ca2+ ionophore was inhibited by anti-CD4 mAb in both T cell populations. Phorbol Esters mitogen-activated protein kinase 8 Homo sapiens