Pub. Date : 1976
PMID : 970052
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The inhibitory effect of 3-diethylaminophenyl-N-methylcarbamate methiodide on rat brain acetylcholinesterase and horse plasma butyrylcholinesterase was studied in vitro. | 3-diethylaminophenyl-N-methylcarbamate methiodide | acetylcholinesterase | Rattus norvegicus |
| 2 | This quaternary carbamate is a more potent inhibitor of acetylcholinesterase than butyrylcholinesterase. | Carbamates | acetylcholinesterase | Rattus norvegicus |
| 3 | Complete inhibition of acetylcholinesterase may be achieved without any inhibition of butyrylcholinesterase, i.e. that 3-diethylaminophenyl-N-methylcarbamate methiodide is a selective inhibitor of acetylcholinesterase. | 3-diethylaminophenyl-N-methylcarbamate methiodide | acetylcholinesterase | Rattus norvegicus |
| 4 | Complete inhibition of acetylcholinesterase may be achieved without any inhibition of butyrylcholinesterase, i.e. that 3-diethylaminophenyl-N-methylcarbamate methiodide is a selective inhibitor of acetylcholinesterase. | 3-diethylaminophenyl-N-methylcarbamate methiodide | acetylcholinesterase | Rattus norvegicus |
| 5 | With increasing doses of carbamate the inhibition of the enzymes in the plasma, erythrocytes, liver, heart, and diaphragm increased while the brain acetylcholinesterase was unaffected. | Carbamates | acetylcholinesterase | Rattus norvegicus |
| 6 | The toxic action of carbamate studied was preferably due to acetylcholin esterase inhibition in the peripheral nervous system and this compound cannot penetrate the blood-brain barrier. | Carbamates | acetylcholinesterase | Rattus norvegicus |