Pub. Date : 1998 Jun 5
PMID : 9603971
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | High glucose treatment activated the tyrosine phosphorylation of both p38 kinase and JNK in a dose- and time-dependent fashion. | Glucose | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | High glucose treatment activated the tyrosine phosphorylation of both p38 kinase and JNK in a dose- and time-dependent fashion. | Tyrosine | mitogen-activated protein kinase 8 | Homo sapiens |
| 3 | In contrast, IGF-I inhibited glucose activation of JNK phosphorylation and JNK activity. | Glucose | mitogen-activated protein kinase 8 | Homo sapiens |
| 4 | In contrast, IGF-I inhibited glucose activation of JNK phosphorylation and JNK activity. | Glucose | mitogen-activated protein kinase 8 | Homo sapiens |
| 5 | IGF-I also inhibited the glucose-induced nuclear translocation of JNK, but did not effect glucose-induced translocation of p38 kinase. | Glucose | mitogen-activated protein kinase 8 | Homo sapiens |
| 6 | Finally, IGF-I inhibition of JNK phosphorylation was blocked by the mitogen-activated protein kinase/extracellular signal-regulated kinase inhibitor, PD98059. | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | mitogen-activated protein kinase 8 | Homo sapiens |