Title : Antitumor effect of the nucleoside analogs 2-chlorodeoxyadenosine and 2',2'-difluorodeoxycytidine on human hepatoma HepG2 cells.

Pub. Date : 1998 Mar

PMID : 9551690






1 Functional Relationships(s)
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1 dFdC showed a more pronounced effect with an inhibition constant (IC50) of 3.98+/-0.03 nM in comparison to 2-CdA with an IC50 of 16.66+/-0.40 nM. gemcitabine cytidine deaminase Homo sapiens