Pub. Date : 1998 Feb 15
PMID : 9473298
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bovine lens aldose reductase (ALR2), which catalyzes the NADPH-dependent reduction of 4-hydroxy-2-nonenal (HNE), is readily inactivated by its own substrate in a time- and concentration-dependent manner. | NADP | lens aldose reductase pseudogene | Bos taurus |
| 2 | Bovine lens aldose reductase (ALR2), which catalyzes the NADPH-dependent reduction of 4-hydroxy-2-nonenal (HNE), is readily inactivated by its own substrate in a time- and concentration-dependent manner. | 4-hydroxy-2-nonenal | lens aldose reductase pseudogene | Bos taurus |
| 3 | Unlike the native enzyme, S-glutathionyl-modified ALR2 is unaffected by HNE, and can be easily reverted to the native form under thiol-reducing conditions. | s-glutathionyl | lens aldose reductase pseudogene | Bos taurus |
| 4 | Unlike the native enzyme, S-glutathionyl-modified ALR2 is unaffected by HNE, and can be easily reverted to the native form under thiol-reducing conditions. | Sulfhydryl Compounds | lens aldose reductase pseudogene | Bos taurus |