Pub. Date : 1998 Feb
PMID : 9463483
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Exposure to IFN-alpha + gamma, FUra, or the combination decreased dTTP pools to 58%, 43%, and 17% of control, respectively. | thymidine 5'-triphosphate | interferon alpha 1 | Homo sapiens |
| 2 | A marked increase in the dATP to dTTP ratio was seen with FUra with or without IFN-alpha + gamma. | thymidine 5'-triphosphate | interferon alpha 1 | Homo sapiens |
| 3 | Thymidylate synthase catalytic activity was reduced to 28% and 24% of control with FUra with or without IFN-alpha + gamma, suggesting that the enhanced dTTP depletion must be due to another mechanism. | thymidine 5'-triphosphate | thymidylate synthetase | Homo sapiens |
| 4 | Thymidylate synthase catalytic activity was reduced to 28% and 24% of control with FUra with or without IFN-alpha + gamma, suggesting that the enhanced dTTP depletion must be due to another mechanism. | thymidine 5'-triphosphate | interferon alpha 1 | Homo sapiens |