Pub. Date : 1998 Feb
PMID : 9448003
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | However, p53 does play a critical role in nocodazole-treated cells which have exited mitotic arrest without undergoing cytokinesis and have thereby adapted. | Nocodazole | transformation related protein 53, pseudogene | Mus musculus |
| 2 | We have determined that in nocodazole-treated, adapted cells, p53 is required during a specific time window to prevent cells from reentering the cell cycle and initiating another round of DNA synthesis. | Nocodazole | transformation related protein 53, pseudogene | Mus musculus |
| 3 | The mechanism of the p53-dependent arrest in nocodazole-treated adapted cells requires the cyclin-dependent kinase inhibitor p21, as p21-/- fibroblasts fail to arrest in response to nocodazole treatment and become polyploid. | Nocodazole | transformation related protein 53, pseudogene | Mus musculus |
| 4 | The mechanism of the p53-dependent arrest in nocodazole-treated adapted cells requires the cyclin-dependent kinase inhibitor p21, as p21-/- fibroblasts fail to arrest in response to nocodazole treatment and become polyploid. | Nocodazole | transformation related protein 53, pseudogene | Mus musculus |