Pub. Date : 1998 Jan
PMID : 9443856
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | UGT2B7 has been shown to catalyze NSAIDs, catechol estrogens, and morphine-3- and -6-glucuronidation. | catechol | UDP glucuronosyltransferase family 2 member B7 | Homo sapiens |
| 2 | UGT2B7 has been shown to catalyze NSAIDs, catechol estrogens, and morphine-3- and -6-glucuronidation. | Morphine | UDP glucuronosyltransferase family 2 member B7 | Homo sapiens |
| 3 | UGT2B7 has been shown to catalyze NSAIDs, catechol estrogens, and morphine-3- and -6-glucuronidation. | and -6 | UDP glucuronosyltransferase family 2 member B7 | Homo sapiens |
| 4 | Our data suggest that UGT2B7 is a major isoform responsible for the glucuronidation of androsterone. | Androsterone | UDP glucuronosyltransferase family 2 member B7 | Homo sapiens |
| 5 | UGT2B7 seems to be a major human isoform responsible for the glucuronidation of opioids of the morphinan and oripavine class and is capable of catalyzing the glucuronidation of both the 3- and 6-hydroxyl moieties on these molecules. | Morphinans | UDP glucuronosyltransferase family 2 member B7 | Homo sapiens |
| 6 | UGT2B7 seems to be a major human isoform responsible for the glucuronidation of opioids of the morphinan and oripavine class and is capable of catalyzing the glucuronidation of both the 3- and 6-hydroxyl moieties on these molecules. | oripavine | UDP glucuronosyltransferase family 2 member B7 | Homo sapiens |
| 7 | Thus, UGT2B7 plays a major role in the conversion of morphine to morphine-6-glucuronide, the potent analgesic metabolite of morphine. | Morphine | UDP glucuronosyltransferase family 2 member B7 | Homo sapiens |
| 8 | Thus, UGT2B7 plays a major role in the conversion of morphine to morphine-6-glucuronide, the potent analgesic metabolite of morphine. | morphine-6-glucuronide | UDP glucuronosyltransferase family 2 member B7 | Homo sapiens |
| 9 | Thus, UGT2B7 plays a major role in the conversion of morphine to morphine-6-glucuronide, the potent analgesic metabolite of morphine. | Morphine | UDP glucuronosyltransferase family 2 member B7 | Homo sapiens |