Title : Oxidative damage in chemical teratogenesis.

Pub. Date : 1997 Dec 12

PMID : 9434860






1 Functional Relationships(s)
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1 Oxidation of DNA may be particularly critical, since transgenic mice with +/- or -/- deficiencies in the p53 tumor suppressor gene, which facilitates DNA repair, are more susceptible to phenytoin and B[a]P teratogenicity. Phenytoin transformation related protein 53, pseudogene Mus musculus