Title : Ligation of major histocompatability complex (MHC) class I molecules on human T cells induces cell death through PI-3 kinase-induced c-Jun NH2-terminal kinase activity: a novel apoptotic pathway distinct from Fas-induced apoptosis.

Pub. Date : 1997 Dec 15

PMID : 9396757






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Strong JNK activity was observed after MHC-I ligation and the activity was completely blocked by wortmannin. Wortmannin mitogen-activated protein kinase 8 Homo sapiens