Title : Phenobarbital causes apoptosis in conditionally immortalized mouse hepatocytes depending on deregulated c-myc expression: characterization of an unexpected effect.

Pub. Date : 1997 Jul 15

PMID : 9230198






2 Functional Relationships(s)
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1 Dissociation of p53 proteins from degrading T antigens followed by a phenobarbital and c-myc-dependent, 15-fold induction of Bax protein, known to activate the apoptotic pathway downstream of p53, occurred in association with this phenomenon. Phenobarbital transformation related protein 53, pseudogene Mus musculus
2 Dissociation of p53 proteins from degrading T antigens followed by a phenobarbital and c-myc-dependent, 15-fold induction of Bax protein, known to activate the apoptotic pathway downstream of p53, occurred in association with this phenomenon. Phenobarbital transformation related protein 53, pseudogene Mus musculus