Title : Calorie restriction induces a p53-independent delay of spontaneous carcinogenesis in p53-deficient and wild-type mice.

Pub. Date : 1997 Jul 15

PMID : 9230186






7 Functional Relationships(s)
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1 We reported previously that calorie restriction (CR) delays spontaneous carcinogenesis in p53-deficient (p53-/-) mice, suggesting that CR modulates carcinogenesis by p53-independent mechanisms. Chromium transformation related protein 53, pseudogene Mus musculus
2 We reported previously that calorie restriction (CR) delays spontaneous carcinogenesis in p53-deficient (p53-/-) mice, suggesting that CR modulates carcinogenesis by p53-independent mechanisms. Chromium transformation related protein 53, pseudogene Mus musculus
3 We reported previously that calorie restriction (CR) delays spontaneous carcinogenesis in p53-deficient (p53-/-) mice, suggesting that CR modulates carcinogenesis by p53-independent mechanisms. Chromium transformation related protein 53, pseudogene Mus musculus
4 CR delayed tumor mortality in p53-/- and p53+/+ mice (mean time to death, 169 and 648 days, respectively) relative to AL feeding (104 and 470 days). Chromium transformation related protein 53, pseudogene Mus musculus
5 CR delayed tumor mortality in p53-/- and p53+/+ mice (mean time to death, 169 and 648 days, respectively) relative to AL feeding (104 and 470 days). Chromium transformation related protein 53, pseudogene Mus musculus
6 The estimated age-specific cancer death rate AL:CR ratios were 4.3 for p53-/- mice and 4.4 for p53+/+ mice. Aluminum transformation related protein 53, pseudogene Mus musculus
7 The estimated age-specific cancer death rate AL:CR ratios were 4.3 for p53-/- mice and 4.4 for p53+/+ mice. Chromium transformation related protein 53, pseudogene Mus musculus