Pub. Date : 1997 May 26
PMID : 9188778
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Singlet oxygen mediates the activation of JNK by UVA radiation in human skin fibroblasts. | Singlet Oxygen | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | Exposure of cells to UVA (300 kJ/m2) led to a 5-fold induction of JNK-activity which was significantly increased in the presence of D2O, an enhancer of the lifetime of singlet oxygen. | Deuterium Oxide | mitogen-activated protein kinase 8 | Homo sapiens |
| 3 | Exposure of cells to UVA (300 kJ/m2) led to a 5-fold induction of JNK-activity which was significantly increased in the presence of D2O, an enhancer of the lifetime of singlet oxygen. | Singlet Oxygen | mitogen-activated protein kinase 8 | Homo sapiens |
| 4 | Sodium azide, a quencher of singlet oxygen, abolished the activation of JNK. | Sodium Azide | mitogen-activated protein kinase 8 | Homo sapiens |
| 5 | Sodium azide, a quencher of singlet oxygen, abolished the activation of JNK. | Singlet Oxygen | mitogen-activated protein kinase 8 | Homo sapiens |
| 6 | Furthermore, photochemically produced singlet oxygen (Rose Bengal plus white light) was found to induce JNK activity. | Singlet Oxygen | mitogen-activated protein kinase 8 | Homo sapiens |
| 7 | Thus, singlet oxygen activates and mediates the UVA-induced activation of JNK. | Singlet Oxygen | mitogen-activated protein kinase 8 | Homo sapiens |