Title : The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation.

Pub. Date : 1997 May 1

PMID : 9171350






1 Functional Relationships(s)
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1 While the stimulation of Erk by alpha6beta4 was suppressed by dominant-negative Shc, Ras and RhoA, the activation of Jnk was inhibited by dominant-negative Ras and Rac1 and by the phosphoinositide 3-kinase inhibitor Wortmannin. Wortmannin mitogen-activated protein kinase 8 Homo sapiens