Title : Involvement of proteasomes in regulating Jak-STAT pathways upon interleukin-2 stimulation.

Pub. Date : 1997 May 30

PMID : 9162019






2 Functional Relationships(s)
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1 We report here that IL-2-induced DNA-binding activity and tyrosine phosphorylation of STAT5 are stabilized by a proteasome inhibitor MG132; however, no detectable ubiquitination of the STAT proteins is observed. benzyloxycarbonylleucyl-leucyl-leucine aldehyde interleukin 2 Homo sapiens
2 We report here that IL-2-induced DNA-binding activity and tyrosine phosphorylation of STAT5 are stabilized by a proteasome inhibitor MG132; however, no detectable ubiquitination of the STAT proteins is observed. benzyloxycarbonylleucyl-leucyl-leucine aldehyde signal transducer and activator of transcription 5A Homo sapiens