Title : Distinct regulation of osmoprotective genes in yeast and mammals. Aldose reductase osmotic response element is induced independent of p38 and stress-activated protein kinase/Jun N-terminal kinase in rabbit kidney cells.

Pub. Date : 1997 May 16

PMID : 9148932






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the present study we asked whether p38 or SAPK/JNK signal synthesis of the osmoprotectant sorbitol in rabbit renal medullary cells (PAP-HT25), analogous to the glycerol system in yeast. Sorbitol mitogen-activated protein kinase 8 Homo sapiens
2 Hyperosmolality (adding 150 mM NaCl) strongly induces phosphorylation of p38 and of c-Jun, a specific target of SAPK/JNK. Sodium Chloride mitogen-activated protein kinase 8 Homo sapiens