Title : Interferon-gamma independently activates the MHC class I antigen processing pathway and diminishes glucose responsiveness in pancreatic beta-cell lines.

Pub. Date : 1997 May

PMID : 9133543






1 Functional Relationships(s)
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1 Exposure of IFN-gamma-treated beta-cells to a peptide aldehyde inhibitor of the proteasome (MG132) significantly attenuated MHC class I cell-surface expression but did not prevent the negative effects of IFN-gamma on glucose responsiveness. benzyloxycarbonylleucyl-leucyl-leucine aldehyde interferon gamma Mus musculus