Title : Hypoglycemia-induced c-Jun phosphorylation is mediated by c-Jun N-terminal kinase 1 and Lyn kinase in drug-resistant human breast carcinoma MCF-7/ADR cells.

Pub. Date : 1997 May 2

PMID : 9115218






2 Functional Relationships(s)
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Protein Name
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1 Experiments with Lyn antisense oligonucleotides demonstrated that Lyn kinase activation was responsible for the activation of JNK1 but not extracellular signal-regulated kinase. Oligonucleotides mitogen-activated protein kinase 8 Homo sapiens
2 These results indicate a possible Ras-dependent signaling pathway involving Lyn kinase and JNK1, which leads to the glucose deprivation-induced responses in MCF-7/ADR cells. Glucose mitogen-activated protein kinase 8 Homo sapiens